Basic Science: insight into the pathogenesis and treatment of pelvic organ prolapse

Workshop 22

Workshop Schedule

14:00

Harold Drutz

14:05

May Alarab

14:45

Steve Abramowitch

15:30

All

16:00

Andrew Feola

16:30

Jan Deprest

17:20

Pamela Moalli

Aims & Objectives

Advanced
240 minutes
Biochemistry & Molecular Biology
MMPs mesh smooth muscle function
Urogynecologists, urologists, PhD students, PhDs, fellows, graduate students

This workshop will update and educate participants on the latest research into the pathogenesis and treatment of pelvic organ prolapse. Talks on pathogenesis will cover intrinsic differences in connective tissue remodeling in women with and without prolapse that favors a degradative response in the former and not the latter. In addition, mechanisms by which maternal birth injury alters the loading environment of the vagina and predisposes to prolapse will be explored. Attendees will learn the appropriateness of different animal models to study prolapse. Finally, the host response to the surgical repair of prolapse using biological vs synthetic meshes will be reviewed as well as a functional approach to selecting a mesh product.