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Category
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Painful Bladder Syndromes/IC |
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Keywords
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Functional Pain Syndrome IC/PBS Visceral Nocicption |
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Target Audience
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Caregivers and Scientists interested in Urologic Chronic Pelvic Pain Syndromes(IC/PBS and CP/CPPS), IBS and other Chronic Pelvic Pain Syndromes |
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Aims and Objectives
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This workshop will describe nociceptive processing from pelvic viscera to the spinal cord, brain stem and the brain under normal conditions and how changes in bidirectional interactions may result in functional pain syndromes. Convergent evidence from patient populations with functional pain syndromes, including urologic chronic pelvic pain syndromes (UCPPS) and irritable bowel syndrome (IBS), suggests alterations in emotional arousal circuits and corticolimbic inhibition circuits, which facilitate and inhibit pain perception, respectively. In persistent pain conditions, it is believed that alterations in these interoceptive influences result in chronic visceral hyperalgesia.
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