Stefan de Wachter ICS Chair
John PFA Heesakkers ICS Chair
14:30
#145 Intravesical application of rebamipide suppresses bladder inflammation and overactivity in a rat model
Presenter: Yasuhito Funahashi
Funahashi Y1, Masaki Y2, Tokunori Y1, Yoshihisa M1, Shun T1, Gotoh M11. Department of Urology, Nagoya University, 2. Department of Urology, National Center for Geriatrics and Gerontology Animal Study, Overactive Bladder, Pharmacology, Painful Bladder Syndrome/Interstitial Cystitis (IC)
14:35
#146 Chloroacetaldehyde, and not acrolein, is the more uro-toxic metabolite of cyclophosphamide and isofosfamide in vitro.
Presenter: Kylie Mills
Mills K1, McDermott C1, Chess-Williams R11. Bond University Cell Culture, Pain, other, Sensory Dysfunction, Urgency/Frequency, Pharmacology
14:40
#147 Involvement of nitric oxide in cyclophosphamide-induced cystitis in rats
Presenter: Yuji Hotta
Hotta Y1, Hattori Y1, Maeda Y1, Kimura K21. Department of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2. Department of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Department of Clinical Pharmacy, Graduate School of Medical Sciences, Nagoya City University Animal Study, Basic Science, Pharmacology, Pathophysiology, Urgency/Frequency
14:45
#148 ANTISENSE OLIGONUCLEOTIDE TARGETING NGF ATTENUATES BLADDER PAIN BEHAVIOR IN RAT WITH EXPERIMENTAL COLITIS
Presenter: Naoki Kawamorita
Kawamorita N1, Yoshikawa S1, Pradeep T1, Mb C2, Yoshimura N11. University of Pittsburgh, 2. Oakland University Painful Bladder Syndrome/Interstitial Cystitis (IC), Animal Study, Pain, Pelvic/Perineal
14:50
#149 Extract of Peucedanum Japonicum, an umbelliferae plant, alleviated acetic acid-induced hypertensive bladder response in rats
Presenter: Yoshihiko Ito
Ito Y1, Kugaya H1, Kojima N1, Hikiyama E1, Onogi H2, Yamada S11. University of Shizuoka, 2. Takara Bio Inc. Animal Study, Overactive Bladder, Other [Plant extract]
14:55
#150 Inhibition of bladder hypersensitivity by interleukin 4 (IL-4) gene therapy using herpes simplex virus (HSV) vectors in rats with cyclophosphamide induced cystitis
Presenter: Tomohiko Oguchi
Oguchi T1, Yokoyama H2, Funahashi Y3, Yoshikawa S3, Nishizawa O2, Goins W F3, Goss J R3, Glorioso J C3, Chancellor M4, Tyagi P3, Yoshimura N31. Nagano Municipal Hospital, 2. Shinshu University, 3. University of Pittsburgh, 4. William Beaumont Hospital Animal Study, Basic Science, Painful Bladder Syndrome/Interstitial Cystitis (IC)
15:00
#151 Activation of transcription factor cAMP response element-binding protein (CREB) signalling in afferent pathways underlies neurogenic bladder dysfunction and chronic pelvic pain in IC/BPS.
Presenter: Anna Malykhina
Pan X1, Lei Q1, Villamor A1, McMillan M1, Malykhina A11. University of Pennsylvania Pain, Pelvic/Perineal, Sensory Dysfunction, Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science
15:05
#152 Mice with Experimental Autoimmune Encephalitis have bladder dysfunction comparable to neurogenic OAB in Multiple Sclerosis.
Presenter: Jan Franken
Franken J1, Boudes M1, Uvin P1, Boeve A2, Voets T2, Hendriks J3, Hellings N3, De Ridder D11. Laboratory of Experimental Urology - UZ Leuven, 2. Laboratory of Ion Channel Physiology - KULeuven, 3. Biomedical Research Institute - Hasselt Animal Study, Basic Science, Detrusor Overactivity, Multiple Sclerosis, Urodynamics Techniques
15:10
#153 INCREASED SUBUROTHELIAL NERVE FIBER AND PURINERGIC P2X3 RECEPTOR EXPRESSIONS IN PATIENTS WITH IDIOPATHIC DETRUSOR OVERACTIVITY AND THEIR RELATIONSHIP WITH BOTULINUM TOXIN A THERAPEUTIC OUTCOME
Presenter: Hsin-Tzu Liu
Liu H1, Jiang Y2, Kuo H21. Department of Urology, Buddhist Tzu Chi General Hospital and Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien, Taiwan, 2. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan Basic Science, Detrusor Overactivity, Other [BoNT-A]
15:15
#154 Gene expression profiling and functional network analysis of benign prostatic hyperplasia model rat
Presenter: Junya Hata
Hata J1, Aikawa K1, Yabe M1, Kawashima Y1, Ishibashi K1, Sasaki S2, Kohri K2, Kojima Y11. Department of Urology, Fukushima Medical University, Fukushima, Japan, 2. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Benign Prostatic Hyperplasia (BPH), Animal Study, Molecular Biology
15:20
#155 Mechanisms inducing hyperexcitability of bladder afferent neurons through prostate-to-bladder afferent cross-sensitization in rats with non-bacterial prostatitis
Presenter: Ryosuke Takahashi
Takahashi R1, Funahashi Y2, Naito S1, Yoshimura N31. Department of Urology, Kyushu University, 2. Department of Urology, Nagoya University, 3. Department of Urology, University of Pittsburgh Detrusor Overactivity, Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC)
15:25
#156 Involvement of prostate-to-bladder afferent cross-sensitization in bladder overactivity in a rat model of prostatic inflammation
Funahashi Y1, Takahashi R2, Tyagi P3, Gotoh M1, Yoshimura N31. Department of Urology, Nagoya University, 2. Department of Urology, Kyusyu University, 3. Department of Urology, University of Pittsburgh Animal Study, Benign Prostatic Hyperplasia (BPH), Overactive Bladder, Pathophysiology
J