Margot Damaser ICS Chair
Steven Mark Finney ICS Chair
16:30
#71 Suppression of detrusor overactivity by herpes simplex virus (HSV) vector-mediated delivery of glial cell line-derived neurotrophic factor (GDNF) in spinal cord injured rats
Presenter: Satoru Yoshikawa
Yoshikawa S1, Oguchi T1, Funahashi Y1, Yoshimura N11. University of Pittsburgh Basic Science, Detrusor Overactivity, Spinal Cord Injury, Overactive Bladder
16:35
#72 Modulation of PGE2-augmented micro-contractions by the non-selective ß-adrenoceptor agonist isoprenaline in isolated strips of rat urinary bladder
Presenter: Claudia Granato
Granato C1, Korstanje C1, Rouget C2, Lluel P2, Palea S2, Gillespie J31. Astellas Pharma Europe B.V., 2. UROsphere S.A.S., 3. Urophysiology Research Group, The Medical and Dental School, Newcastle University Pharmacology, Pre-Clinical testing, Physiology
16:40
#73 The Influence of the mucosa and bladder outlet obstruction on the effect of cyclooxygenase inhibitor, indomethacin, on spontaneous contractile activity in the rat bladder
Presenter: Keiko Nagase
Nagase K1, Akino H1, Yokokawa R1, Ishida H1, Yokoyama O11. The Department of Urology, Faculty of Medical Science, University of Fukui Animal Study, Basic Science, Bladder Outlet Obstruction , Pharmacology
16:45
#74 Modulation of PGE2-augmented non-voiding activity by ß3-adrenoceptor agonist mirabegron in conscious rats
Granato C1, Korstanje C1, Guilloteau V2, Lluel P2, Palea S2, Gillespie J31. Astellas Pharma Europe B.V., 2. UROsphere S.A.S., 3. Urophysiology Research Group, The Medical and Dental School, Newcastle University Detrusor Overactivity, Animal Study, Pharmacology
16:50
#75 Purinergic contractile effects mediated by cholinergic transmission in the rat urinary bladder
Presenter: Patrik Aronsson
Aronsson P1, Winder M1, Johnsson M1, Carlsson T1, Tobin G11. University of Gothenburg Animal Study, Basic Science, Pharmacology
16:55
#76 A comparison of the functional properties of human detrusor smooth muscle from paediatric and adult patients with stable bladders
Presenter: Christopher Fry
Johal N1, Cuckow P1, Wood D2, Fry C31. Great Ormond St Hospital, London, 2. University College London Hospital, 3. University of Surrey Physiology, Pediatrics, Pathophysiology, Detrusor Overactivity, Biomechanics
17:00
#77 Complex signal interactions between the different layers of the urothelium of the rat
Presenter: James Gillespie
Gillespie J1, Wright J1, McNeill C1, Eastham J1, Birder L21. Newcastle, UK, 2. Pittsburgh, USA Pharmacology, Basic Science, Physiology
17:05
#78 UROTHELIUM INHIBITS ß-ADRENOCEPTOR-MEDIATED RELAXATION IN HUMAN DETRUSOR SMOOTH MUSCLE VIA cAMP- and P2 PURINOCEPTOR-DEPENDENT MECHANISM
Presenter: Yasuhiko Igawa
Igawa Y1, Kumano S1, Aizawa N1, Ito H1, Sugiyama R1, Homma Y21. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, 2. Department of Urology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan Pharmacology, Basic Science, Molecular Biology, Overactive Bladder, Physiology
17:10
#79 The function and regulation of stress-induced acetylcholine release from the bladder urothelium
Fry C1, McLatchie L11. University of Surrey Physiology, Painful Bladder Syndrome/Interstitial Cystitis (IC), Pharmacology, Urgency/Frequency, Basic Science
17:15
#80 Alterations in mediator release from the urothelium in a rat model of cerebral infarction: effect of the ß3-agonist BRL37344
Presenter: Ryusei Yokokawa
Yokokawa R1, Akino H1, Nagase K1, Zha X1, Yokoyama O11. University of Fukui Animal Study, Basic Science, Detrusor Overactivity, Pharmacology
17:20
#81 Additive effects for increased bladder storage function with the antimuscarinic drug solifenacin and the selective ß3-adrenergic agonist mirabegron in two rat models for in vivo bladder function.
Presenter: Cees Korstanje
Korstanje C1, Someya A2, Hiroshi Y2, Noguchi Y2, Ukai M2, Suzuki M2, Sasamata M11. Transl.& Devel. Pharmacol. Dept, Astellas Pharma EU, Leiden, NL, 2. Pharmacology Labs, Astellas Pharma Inc., Tsukuba, Japan Animal Study, Detrusor Overactivity, Voiding Dysfunction
17:25
#82 Modulation of urothelial function and afferent sensitivity by Neurokinin A
Presenter: Luke Grundy
Grundy L1, Mills K1, Grundy D2, Chess-Williams R11. Bond University, 2. Sheffield University Pharmacology, Physiology, Neuromodulation, Basic Science, Animal Study
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