Advanced clinical and research methods for unravelling the relationship between pathophysiology and the success of OAB treatment

Workshop 25

Workshop Schedule

09:00

Cara Tannenbaum

09:15

Ann Hanna-Mitchell

09:45

Rufus Cartwright

10:15

Cara Tannenbaum

10:30

None

11:00

All

11:15

None

11:30

None

11:45

Cara Tannenbaum

Aims & Objectives

Advanced
180 minutes
LUT Physiology
Pathophysiology Treatment of idiopathic overactive bladder Biomarkers
Urologists, urogynecologists, clinical trialists, basic science researchers, pharmaceutical industry, and outcomes researchers
This workshop aims to create a framework for clinicians and researchers to classify OAB patients according to underlying pathophysiology. We will review the 4 current pathophysiologic theories underlying idiopathic OAB symptoms: the urothelial/suburothelial hypothesis, the myogenic hypothesis, bladder ischemia, and stress-related/perceptual disturbances originating in the central nervous system. Participants will be exposed to different clinical screening strategies and/or biomarkers to identify patients with each pathophysiologic sub-type of idiopathic OAB. Evidence on the relationship between pathophysiology and the success of OAB treatment will be critically appraised in the context of validating a new clinical classification algorithm.