|
Keywords
|
Pathophysiology Treatment of idiopathic overactive bladder Biomarkers |
|
Target Audience
|
Urologists, urogynecologists, clinical trialists, basic science researchers, pharmaceutical industry, and outcomes researchers |
|
Aims and Objectives
|
This workshop aims to create a framework for clinicians and researchers to classify OAB patients according to underlying pathophysiology. We will review the 4 current pathophysiologic theories underlying idiopathic OAB symptoms: the urothelial/suburothelial hypothesis, the myogenic hypothesis, bladder ischemia, and stress-related/perceptual disturbances originating in the central nervous system. Participants will be exposed to different clinical screening strategies and/or biomarkers to identify patients with each pathophysiologic sub-type of idiopathic OAB. Evidence on the relationship between pathophysiology and the success of OAB treatment will be critically appraised in the context of validating a new clinical classification algorithm.
|