ICS 2014 Scientific Podium Poster Session S22 - Mechanisms Underlying Pain and Cystitis

Speakers
	Wednesday 22nd October 2014
	16:30 - 18:00
	Room B1
L Lori A Birder ICS Chair M Masayuki Takeda ICS Chair J Jorge Haddad ICS Chair

17:00

#348 Hippuric acid: A Biomarker for Bladder Pain Syndrome.

Presenter: Rhiannon Bray

Bray R¹, Jimenez B², MacIntyre D³, Cartwright R⁴, Franklin-Nembhard L¹, Digesu A¹, Fernando R¹, Holmes E², Bennett P³, Khullar V¹
1. Department of Urogynaecology, St Mary’s Hospital, Imperial College, London, 2. Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, 3. Department of Surgery and Cancer, Parturition Research Group, Institute of Reproduction and Developmental Biology, Imperial College London, 4. Dept of Urogynaecology, St Mary's Hospital, London & Dept of Epidemiology & Biostatistics, Imperial College London
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pathophysiology, Molecular Biology, Basic Science, Biochemistry

17:05

#349 Urothelial dysfunction and chronic inflammation in patients with bladder outlet obstruction and different bladder dysfunction

Presenter: Chung-Cheng Wang

Wang C¹, Lee C², Kuo H²
1. Department of Urology, En Chu Kong Hospital, New Taipei, Taiwan, 2. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Benign Prostatic Hyperplasia (BPH), Bladder Outlet Obstruction , Pathophysiology

17:10

#350 Urothelial dysfunction and chronic inflammation in patients with chronic interstitial cystitis with and without Hunner’s lesion

Presenter: Jia-Fong Jhang

Chen S¹, Jhang J¹, Kuo H¹
1. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Pathophysiology, Painful Bladder Syndrome/Interstitial Cystitis (IC), Molecular Biology

17:15

#351 A novel animal model of chronic urothelial injury and bladder pain hypersensitivity induced by intermittent infusion of protamine sulphate into the bladder in rats: the involvement of prostaglandin E2 and EP1 receptor activation

Presenter: Hiroki Okada

Okada H¹, Tyagi P¹, Kawamorita N¹, Majima T¹, Chancellor M B², Yoshimura N¹
1. Department of Urology, University of Pittsburgh, 2. Department of Urology, William Beaumont Hospital
Animal Study, Detrusor Overactivity, Painful Bladder Syndrome/Interstitial Cystitis (IC), Sensory Dysfunction

17:20

#352 Recovery of Urothelial Barrier Function by Rebamipide

Presenter: Yasuhito Funahashi

Funahashi Y¹, Yoshida M², Yamamoto T¹, Matsukawa Y¹, Takai S¹, Gotoh M¹
1. Nagoya University, 2. National Center for Geriatrics and Gerontology
Animal Study, Basic Science, Painful Bladder Syndrome/Interstitial Cystitis (IC)

17:25

#353 A novel cystometry method combined with bladder ultrasonography reveals rapid decrease of bladder capacity and compliance in mice LPS-induced cystitis

Presenter: Kentaro Takezawa

Takezawa K¹, Kondo M¹, Kiuchi H¹, Soda T¹, Takao T¹, Miyagawa Y¹, Tsujimura A¹, Nonomura N¹, Shimada S¹
1. Osaka University Graduate School of Medicine
Animal Study, Basic Science, Physiology

17:30

#354 Proteomics of ketamine cystitis and interstitial cystitis – a way to search for different pathophysiology between diseases with similar bladder symptoms

Presenter: Chung-Cheng Wang

Yang H¹, Wang C², Zhai W¹, Jiang Y³, Kuo H³
1. Department of Research, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, 2. Department of Urology, En Chu Kong Hospital, New Taipei, Taiwan, 3. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pathophysiology, Basic Science

17:35

#355 Reduced expression of estrogen receptor-alpha in patients with bladder pain syndrome/interstitial cystitis

Presenter: Akira Furuta

Furuta A¹, Suzuki Y², Kimura S¹, Egawa S¹, Yoshimura N³
1. Jikei University School of Medicine, Tokyo, JAPAN, 2. Tokyo Rehabilitation Hospital, Tokyo, JAPAN, 3. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pathophysiology, Pain, Pelvic/Perineal

17:40

#356 SYSTEMIC ADMINISTRATION OF AN ACID-SENSING ION CHANNEL BLOCKER ALLEVIATES BLADDER HYPERACTIVITY INDUCED BY INTRAVESICAL ACETIC ACID IRRITATION IN MICE

Presenter: Mitsuharu Yoshiyama

Yoshiyama M¹, Kobayashi H¹, Takeda M¹
1. Department of Urology, University of Yamanashi Interdisciplinary Graduate School of Medicine and Engineering
Overactive Bladder, Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC), Detrusor Overactivity, Pharmacology

17:45

#357 Study of oestradiol effect upon ATP release in primary pig urothelial cell culture: a possible mechanism of action for topical vaginal oestradiol?

Presenter: Ying Cheng

Cheng Y¹, Moore K H¹
1. St George Hospital, University of New South Wales, Sydney, Australia
Basic Science, Cell Culture, Female, Urgency Urinary Incontinence, Hormone Therapy

17:50

#358 Direct evidence for significant contribution of imidafenacin excreted in the urine to the bladder-selective pharmacological effects

Presenter: Yoshihiko Ito

Ito Y¹, Takahashi A¹, Kuraoka S¹, Endo S¹, Yamada S¹
1. University of Shizuoka
Animal Study, Basic Science, Pharmacology, Overactive Bladder

17:55

#359 Pannexin 1 channels participate in urothelial ATP release and signaling.

Presenter: Hiromitsu Negoro

Negoro H¹, Liou L², Spray D³, Thi M³, Ogawa O⁴, Suadicani S³
1. Kyoto University Graduate School of Medicine, and Albert Einstein College of Medicine, 2. Cambridge Health Alliance, 3. Albert Einstein College of Medicine, 4. Kyoto University Graduate School of Medicine
Basic Science, Biomechanics, Molecular Biology, Pharmacology, Physiology

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Mechanisms Underlying Pain and Cystitis

Scientific Podium Poster Session S22

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