ICS 2014 Scientific Open Discussion Poster Session S37

Pharmacology

Speakers
	Scientific Open Discussion Poster Session S37
	Thursday 23rd October 2014
	13:30 - 14:30
	Poster Area
	Lunch provided
T Thais Palma Poster Pilot M Marcy Lancia Pereira Poster Pilot C Carlos Errando Poster Pilot T Tom P Rosenbaum Poster Pilot M Myung-Soo Choo ICS Chair

Session Schedule

13:30

#558 INCREASED PROSTATE SMOOTH MUSCLE CONTRACTIONS AND REDUCED RELAXATIONS IN MIDDLE-AGED RATS.

Calmasini F B¹, Silva F H¹, Alexandre E C¹, Rodrigues R L¹, Báu F R¹, Antunes E¹
1. University of Campinas (UNICAMP)
Benign Prostatic Hyperplasia (BPH), Pharmacology, Basic Science

13:30

#559 BAY 41-2272, a soluble guanylate cyclase stimulator, improves bladder function in partial bladder outlet obstructed mice

Lancia Pereira M¹, Arturo Levi D´Ancona C¹, Saragossa Ramos-Filho A C², Rojas-Moscoso J A², Antunes E²
1. Urology / Surgery Department - Faculty of Medical Sciences - UNICAMP, 2. Pharmacology - Faculty of Medical Sciences - UNICAMP
Bladder Outlet Obstruction , Overactive Bladder, Pathophysiology, Animal Study

13:30

#560 Therapeutic effects of intravesical onabotulinumtoxinA injection on IC/BPS refractory to conventional treatment - a randomized, double blind, placebo controlled study

Kuo Y¹, Lee C², Jiang Y², Kuo H²
1. Department of Urology, Taipei City Hospital, Taipei, Taiwan, 2. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Painful Bladder Syndrome/Interstitial Cystitis (IC), Clinical Trial, Pharmacology

13:30

#561 Botulinum toxin A urethral sphincter injection for non-obstructive voiding dysfunction – A randomized, double-blind, placebo control, multicenter study

Wang C¹, Jhang J², Jiang Y², Kuo H²
1. Department of Urology, En Chu Kong Hospital, New Taipei, Taiwan, 2. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Voiding Dysfunction , Pharmacology, Clinical Trial

13:30

#562 Resveratrol improves systemic oxidative stress and lower urinary tract dysfunction in obese mice

Alexandre E C¹, Calmasini F B¹, Majolli D¹, Silva F H¹, Vargas C², Delbin M A², Antunes E¹
1. Faculty of Medical Sciences, Department of Pharmacology, University of Campinas, 2. Institute of Biology, University of Campinas
Detrusor Overactivity, Pharmacology, Voiding Dysfunction

13:30

#563 Patient initial treatment preference is anticholinergic therapy over onabotulinumtoxinA for urgency urinary incontinence regardless of symptom severity

Jahromi M S¹, Alonzo D¹, Gomez C S¹
1. University of Miami
Incontinence, Pharmacology, Questionnaire

13:30

#564 The efficacy and tolerability of tarafenacin, a new muscarinic acetylcholine receptor M3 antagonist in patients with overactive bladder; randomized, double- blind, placebo-controlled phase 2 study

Park J¹, Song M¹, Kim J H², Han J³, Lee J Z⁴, Oh S⁵, Seo J T⁶, Choi J B⁷, Park S⁸, Kim K S¹, Park W H⁹, Choo M¹
1. Department of Urology, Asan Medical Center, University of Ulsan College of Medicine,Seoul, Korea, 2. Department of Urology, Severance Hospital, Yonsei University College of Medicine,Seoul, Korea, 3. Department of Urology, Pusan National University Yangsan Hospital, Pusan, 4. Department of Urology, Pusan National University Hospital, Busan, Korea, 5. Department of Urology, Seoul National University Hospital, Seoul, Korea, 6. Department of Urology, Cheil General Hospital & Women's Helathcare Center, Kwandong University College of Medicine, Seoul, Korea,, 7. Department of Urology, Ajou University Hospital, Suwon, Korea, 8. Department of Urology, Ulsan university hospital, Ulsan, Korea, 9. 9Department of Urology, Inha University College of Medicine, Incheon, Korea
Overactive Bladder, Clinical Trial, Constipation, Pharmacology, Prospective Study

13:30

#565 The efficacy and safety of flexible dose imidafenacin (0.2mg or 0.4mg), for the treatment of overactive bladder and nocturia

Yamanishi T¹, Kaga K¹, Fuse M¹, Uchiyama T¹, Shibata C¹, Sakakibara R²
1. Dokkyo Medical University, Continence Center, 2. Sakura Medical Center, Toho University
Overactive Bladder, Nocturia, Pharmacology

13:30

#566 Mirabegron in treatment of neurological overactive bladder in multiple sclerosis patients

Risi O¹, Cito L¹, Andretta E², Conigliaro R³, Augello G³
1. Neuro-urology DPT Treviglio Hospital, 2. Urology DPT Dolo-Mirano Hospital, 3. Neurology Siracusa Hospital
Multiple Sclerosis, Overactive Bladder, Urgency Urinary Incontinence

13:30

#567 Does bacterial vaccine become clinically significant in neurogenic bladder patients at clean intermittent catheterization?

Ordaz Jurado G¹, Bonillo Garcia M¹, Betancourt Hernández J¹, Arlandis Guzman S¹, Avargues Pardo A¹, Broseta Rico E¹, Boronat Tormo F¹
1. Hospital Universitari i Politècnic La Fe Valencia
Pharmacology, Quality of Life (QoL), Infection, Urinary Tract

13:30

#568 Characterization of muscarinic receptor binding of fesoterodine after oral administration in rats

Yamada S¹, Yoshida A¹, Ito Y¹
1. University of Shizuoka
Pharmacology, Basic Science, Overactive Bladder

13:30

#569 Intravesical instillation of Liposome encapsulated onabotulinumtoxinA for patients with overactive bladder – A pilot clinical study

Jiang Y¹, Lee C¹, Kuo H¹
1. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Overactive Bladder, Pharmacology, Clinical Trial

13:30

#570 The effects of chronic nitric oxide synthesis inhibition on bladder function in partial outlet obstructed mice

Lancia Pereira M¹, Arturo Levi D´Ancona C¹, Rojas-Moscoso J A², Saragossa Ramos-Filho A C², Zakia Taufic Mónica F², Antunes E²
1. Urology / Surgery Department - Faculty of Medical Sciences - UNICAMP, 2. Pharmacology - Faculty of Medical Sciences - UNICAMP
Male, Bladder Outlet Obstruction , Pharmacology, Animal Study, Pathophysiology

13:30

#571 How long can antimuscarinic treatment be effective in treatment of overactive bladder – analysis of the predictive factors
Delegates Choice Award

Hsiao S¹, Liao C², Kuo H³
1. Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, New Taipei, Taiwan, 2. Department of Urology, Cardinal Tien Hospital and School of Medicine, Fu-Jen Catholic University, New Taipei, Taiwan, 3. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Pharmacology, Urgency/Frequency, Detrusor Overactivity

13:30

#572 Predictors of urinary retention in patients undergoing open renal surgery with thoracic epidurally analgesia: A pooled analysis

Burkhard F¹, Wuethrich P Y²
1. University Bern, 2. University Bern, Department of Anaesthesiology and Pain Medicine
Voiding Dysfunction , Detrusor Hypocontractility, Surgery

13:30

#573 Oral administration of prosultiamine improved the symptoms in patients with overactive bladder associated with HTLV-1-related myelopathy/tropical spastic paraparesis, and also reduced urinary biomarkers.

Matsuo T¹, Nakamura T², Miyata Y¹, Ohba K¹, Sakai H¹
1. Department of Urology and Renal Transplantation, Nagasaki University School of Medicine, 2. Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University
Pharmacology, Clinical Trial, Overactive Bladder, Neuropathies: Peripheral

13:30

#574 The effects of tolterodine and 5-hydroxymethyl tolterodine (5HMT) on carbachol-induced contraction in human bladder smooth muscles in normal state and in detrusor overactivity associated with benign prostatic hyperplasia

Yamanishi T¹, Fuse M¹, Kaga K¹, Shibata C¹, Uchiyama T¹, Sakakibara R²
1. Dokkyo Medical University, Continence Center, 2. Sakura Medical Center, Toho University
Benign Prostatic Hyperplasia (BPH), Detrusor Overactivity, Pharmacology, Urgency Urinary Incontinence, Overactive Bladder

13:30

#575 Superior Efficacy of Combination Pharmacotherapy for Treatment of Neurogenic Detrusor Overactivity

Fraser M O¹, Lloyd J C², Le N B², Wiener J S², Dolber P C³
1. Duke University and Durham Veterans Affairs Medical Centers, Institute for Medical Research, 2. Duke University Medical Center, 3. Duke University and Durham Veterans Affairs Medical Centers
Pharmacology, Spinal Cord Injury, Detrusor Overactivity, Basic Science, Animal Study

13:30

#576 Persistence with mirabegron in patients with overactive bladder : A Comparative study of mirabegron and antimuscarinics.

Ogihara K¹, Kaguyama H¹, Sakamoto H¹, Aonuma K¹, Matsuda K¹, Nakahira Y¹, Yanaihara H¹, Asakura H¹
1. Saitama Medical University
Overactive Bladder, Pharmacology, Voiding Dysfunction

13:30

#577 USEFULL OF INTRAVESICAL INSTILLATION OF HYALURONIC ACID AND CHONDROITIN SULPHATE IN PREVENTING RECURRENT BACTERIAL CYSTITIS

Adile B¹, Calagna G², Adile G², Granese R³, Polito S⁴, Saitta S⁵, Speciale P¹, Gugliotta G¹
1. Urogynecology Unit, VillaSofia-Cervello Hospital – Palermo, Italy, 2. Departiments of Obstetrics and Gynecology, “University Hospital P.Giaccone” – Palermo, Italy, 3. Departiments of Obstetrics and Gynecology, “University Hospital Martino” – Messina, Italy, 4. Obstetrics and Gynaecology Unit, Casa di Cura “Triolo-Zancla”, Palermo, Italy, 5. School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University Hospital “G. Martino”, Messina, Italy
Infection, Urinary Tract, Prevention, Quality of Life (QoL)

13:30

#578 A comparative study on the efficacy of solifenacin succinate in patients with urinary frequency with or without urgency

Han J¹, Lee K², Park W H³, Park C H⁴, Lee J G⁵, Lee J Z⁶, Kim D Y⁷, Na Y G⁸, Kwon D D⁹, Kim K S¹⁰, Park S¹¹, Choo M¹⁰
1. Pusan National University Yangsan Hospital, 2. Samsung Medical Center, Sungkyunkwan University School of Medicine, 3. Inha University College of Medicine, 4. Keimyung University School of Medicine, 5. Korea University Hospital, 6. Pusan National University Hospital, 7. Catholic University of Daegu School of Medicine, 8. Chungnam National University School of Medicine, 9. Chonnam National University Medical School, 10. University of Ulsan College of Medicine, Asan Medical Center, 11. Ulsan University Hospital, University of Ulsan College of Medicine
Overactive Bladder, Urgency/Frequency, Pharmacology

13:30

#579 Evaluating the Magnitude of Improvements in Patient-Reported Outcomes by Age in Overactive Bladder Patients: A Pooled Analysis of Two Mirabegron Clinical Trials

Lipsitz D¹, Frankel J², Berner T³, Reckard G³, Eaddy M⁴, Campbell C⁴
1. Carolina Clinical Trials, 2. Seattle University Research Center, 3. Astellas Scientific and Medical Affairs, Inc, 4. Xcenda, LLC
Overactive Bladder, Outcomes Research Methods, Quality of Life (QoL)

13:30

#580 100 UNITS OF INTRA-DETRUSOR ONABOTULINUMTOXIN A FOR IDIOPATIC OVERACTIVE BLADDER PATIENTS REFRACTORY TO ANTIMUSCARINIC THERAPY
Delegates Choice Award

Salazar A¹, Iglesias T², Svicarovic I², Acuña A¹, Vicherat C¹, Miranda A¹
1. Urology Deparment - Chilean Air Force Hospital _ Universidad Mayor - Chile, 2. Universidad de Los Andes - Chile
Detrusor Overactivity, Urgency Urinary Incontinence, Overactive Bladder

13:30

#581 Combined intravesical trigonal and urethral injections of onabotulinumtoxinA in the treatment of patients with hypersensitive bladder and voiding dysfunction – a pilot study

Chen S¹, Jiang Y¹, Liao C², Kuo H¹
1. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan, 2. Department of Urology, Cardinal Tien Hospital and School of Medicine, Fu-Jen Catolic University, New Taipei
Overactive Bladder, Pharmacology, Voiding Dysfunction

13:30

#582 A Prospective, Multicenter, Observational Study to Estimate the Dry Mouth in Overactive Bladder Patients Treated with Solilfenacin

Park J¹, Chun J¹, Park W H², Kim K S¹, Park S³, Han J⁴, Oh S⁵, Kim J C⁶, Choi J B⁷, Kim J H⁸, Seo J T⁹, Choo M¹
1. Department of Urology, Asan Medical Center, University of Ulsan College of Medicine,Seoul, Korea, 2. Department of Urology, Inha University College of Medicine, Incheon, Korea, 3. Department of Urology, Ulsan university hospital, Ulsan, Korea, 4. Department of Urology, Pusan National University Yangsan Hospital, Pusan, 5. Department of Urology, Seoul National University Hospital, Seoul, Korea, 6. Department of Urology, Bucheon St. Mary’s Hospital, The Catholic University of Korea, Bucheon, Korea, 7. Department of Urology, Ajou University Hospital, Suwon, Koreaa, 8. Department of Urology, Severance Hospital, Yonsei University College of Medicine,Seoul, Korea, 9. Department of Urology, Cheil General Hospital & Women's Helathcare Center, Kwandong University College of Medicine, Seoul, Korea,
Urgency/Frequency, Overactive Bladder, Prospective Study, Clinical Trial, Questionnaire

13:30

#583 BETA-3 RECEPTOR AGONIST, MIRABEGRON RELAXES ISOLATED PROSTATE FROM HUMAN AND RABBIT: NEW THERAPEUTIC INDICATION

Calmasini F B¹, Candido T T¹, Alexandre E C¹, D'Ancona C², Silva D², de Oliveira M A³, De Nucci G⁴, Antunes E¹, Mónica F Z¹
1. Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil, 2. Divison of Urology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil, 3. Department of Pharmacology, (UNICAMP), Campinas, Institute of Research and Development, University of Vale do Paraíba (UNIVAP) Sao Paulo, Brazil, 4. Department of Pharmacology, (UNICAMP), Campinas, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo (USP), Sao Paulo, Brazil
Benign Prostatic Hyperplasia (BPH), Molecular Biology, Overactive Bladder

13:30

#584 COMBINATION THERAPY WITH SOLIFENACIN 10 mg AND TAMSULOSIN 0,4 mg ORAL FOR URGENCY URINARY INCONTINENCE IN MEN. EFFICACY AND SAFETY RESULTS

Manasia P¹, Alcover J², Benages J¹, Miguel J¹, Gonzalez P¹
1. Department of Urology, Hospital XARXA Santa Tecla Tarragona Spain, 2. Department of Urology, Corachan Hospital Barcelone Spain
Benign Prostatic Hyperplasia (BPH), Nocturia, Pharmacology, Urgency Urinary Incontinence, Bladder Outlet Obstruction

13:30

#585 PROPIVERINE ER AND EFFECTS OF FLEXIBLE DOSING IN 1335 PATIENTS WITH OAB: RESULTS OF A NON-INTERVENTIONAL STUDY

Eisenhardt A¹, Schneider T¹, Murgas S², Oelke M³
1. Urology Clinic Mülheim, Germany, 2. Apogepha Arzneimittel GmbH Dresden, Germany, 3. Hannover Medical School, Germany
Overactive Bladder, Pharmacology, Urgency Urinary Incontinence, Urgency/Frequency

International Continence Society

Pharmacology

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