ICS 2016 Scientific Podium Short Oral Session S6 - Neurophysiology and Pharmacology

Neurophysiology and Pharmacology

Scientific Podium Short Oral Session S6

Speakers
	Wednesday 14th September 2016
	10:30 - 12:00
	Hall D5 Capacity: 200
F Francisco Cruz ICS Chair H Hidehiro Kakizaki ICS Chair

Session Schedule

10:30

#55 EFFECT OF ALPHA1 ADRENOCEPTOR ANTAGONIST NAFTOPIDIL ON THE ARGININE-VASOPRESSIN SECRETION AND URINE VOLUME IN CENTRALLY NORADRENALINE-ADMINISTERED RATS

Shimizu S¹, Shimizu T¹, Yamamoto M¹, Higashi Y¹, Nakamura K¹, Tsounapi P², Liu N¹, Honda M², Takenaka A², Saito M¹
1. Department of Pharmacology, Kochi Medical School, Kochi University, 2. Division of Urology, Tottori University School of Medicine
Animal Study, Basic Science, Nocturia, Pharmacology

10:37

#56 PHARMACOLOGICAL CHARACTERIZATION OF BRAIN SEROTONIN RECEPTOR SUBTYPES INVOLVED IN BOMBESIN-INDUCED FREQUENT URINATION IN RATS

Shimizu T¹, Shimizu S², Wada N³, Takai S³, Shimizu N³, Higashi Y², Kadekawa K³, Majima T³, Saito M², Yoshimura N³
1. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA and Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 2. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 3. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA
Animal Study, Basic Science, Male, Pharmacology

10:45

#57 The role of brain brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in bladder and urethral dysfunction in mice with spinal cord injury

Wada N¹, Shimizu T¹, Shimizu N¹, Tyagi P¹, Kanai A², de Groat W³, Kakizaki H⁴, Yoshimura N¹
1. The Department of Urology, University of Pittsburgh, 2. The Department of Medicine, University of Pittsburgh, 3. The Department of Pharmacology, University of Pittsburgh, 4. The Department of Renal and Urologic Surgery, Asahikawa Medical Univeristy
Animal Study, Detrusor Overactivity, Spinal Cord Injury, Voiding Dysfunction , Pathophysiology

10:52

#58 SUPRASPINAL DOPAMINE UPTAKE INHIBITION INFLUENCES THE MICTURITION REFLEX IN URETHANE-ANESTHETIZED RATS

Tsounapi P¹, Yoshimura N², Kawamoto B¹, Hikita K¹, Shimizu T³, Honda M¹, Saito M³, Chancellor M⁴, Takenaka A¹
1. Department of Urology, Tottori University Faculty of Medicine, 2. Department of Urology, University of Pittsburgh School of Medicine, 3. Department of Pharmacology, Kochi Medical School, 4. Department of Urology, William Beaumont Hospital
Basic Science, Pharmacology, Physiology

11:00

#59 Action of naftopidil on spinal serotonergic neurotransmission for inhibition of the micturition reflex in rats

Nishijima S¹, Sugaya K¹, Kadekawa K¹, Ashitomi K¹, Ueda T², Yamamoto H³, Hattori T⁴
1. Southern Knights' Laboratory, 2. Institute for Animal Experiments, Faculty of Medicine, University of the Ryukyus., 3. Department of Biochemistry, Graduate School of Medicine, University of the Ryukyus., 4. Department of Medical Affairs, Asahi Kasei Pharma Corporation.
Pharmacology, Overactive Bladder, Animal Study

11:07

#60 Post-trauma bladder management strategy influences lower urinary tract dysfunction after spinal cord injury in the mouse model

Wada N¹, Shimizu T¹, Shimizu N¹, Takai S¹, Tyagi P¹, Kakizaki H², Yoshimura N¹
1. The Department of Urology, University of Pittsburgh, 2. The Department of Renal and Urologic Surgery, Asahikawa Medical University
Animal Study, Spinal Cord Injury, Detrusor Overactivity, Pathophysiology

11:15

#61 Inhibition of p75 neurotrophin receptors reduces neural degeneration and lower urinary tract dysfunction following spinal cord injury

Ikeda Y¹, Zabbarova I¹, Kullmann F A¹, Birder L¹, Carder E¹, Wipf P¹, Kanai A¹
1. University of Pittsburgh
Animal Study, Pharmacology, Pathophysiology, Spinal Cord Injury, Detrusor Overactivity

11:22

#62 Correlation of sacral nerve lead targeting and urological efficacy: motor mapping, electrode position, and stimulation amplitude

Zirpel L¹, Su X¹, Wotton J², Reinking N¹, Steiner A¹, Nelson D E¹, Brink T¹
1. Medtronic, 2. Gustavus Adolphus University
Animal Study, Imaging, Neuromodulation, Pre-Clinical testing, Physiology

11:30

#63 Hyperexcitability of capsaicin sensitive bladder afferent neurons from mice with neurogenic detrusor overactivity induced by spinal cord injury

Shimizu T¹, Majima T², Kadekawa K², Shimizu N², Wada N², Takai S², Tyagi P², Saito M³, Yoshimura N²
1. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA and Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 2. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA, 3. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan
Animal Study, Basic Science, Detrusor Overactivity, Physiology, Spinal Cord Injury

11:37

#64 Herpes simplex virus (HSV) vector-mediated tracing and labelling of different populations of bladder afferent neurons in normal and spinal cord injured mice

Shimizu N¹, Goins W², Takai S³, Shimizu T³, Wada N³, Hirayama A⁴, Uemura H⁵, Tyagi P³, Glorioso J², Yoshimura N³
1. Dept of Urology- University of Pittsburgh, Kindai University Hospital, Faculty of Medicine, 2. Dept of Microbiology & Molecular Genetics-University of Pittsburgh, 3. Dept of Urology- University of Pittsburgh, 4. Dept of Urology- Kindai University Nara Hospital, Faculty of Medicine, 5. Dept of Urology-Kindai University Hospital, Faculty of Medicine
Animal Study, Detrusor Overactivity, Imaging, New Instrumentation, Spinal Cord Injury

11:45

#65 Bladder reinnervation by nerve transfer using a primarily motor donor nerve (femoral nerve branches) induces increased sympathetic bladder innervation

Barbe M F¹, Gomez-Amaya S M¹, Dachert S¹, Lewis J¹, Wood M W¹, Braverman A S¹, Ruggieri, Sr. M R¹
1. Temple University School of Medicine
Animal Study, Basic Science, Rehabilitation, Spinal Cord Injury, Surgery

11:52

#66 Role of microglia in the spinal cord in colon-to-bladder neural crosstalk in a rat model of colitis.

Majima T¹, Funahashi Y¹, Kawamorita N², Matsukawa Y¹, Yamamoto T¹, Yoshimura N³, Gotoh M¹
1. Nagoya University Graduate School of Medicine, 2. Tohoku University Graduate School of Medicine, 3. University of Pittsburgh
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pathophysiology, Animal Study