ICS 2016 Scientific Podium Short Oral Session S8

Systemic Models

Scientific Podium Short Oral Session S8

Speakers
	Wednesday 14th September 2016
	14:05 - 15:35
	Hall C Capacity: 1500
M Motoaki Saito ICS Chair G Gommert A van Koeveringe ICS Chair

Session Schedule

14:05

#155 The Vitamin D analogue Bxl-628 alters excitation contraction coupling in the isolated bladder in aged wildtype mice differently compared to bladders from age-matched transgenic Alzheimer’s disease mice

Hohnen R¹, Stouthandel M E J¹, den Hartog G J M², Meriaux C¹, Van Koeveringe G³
1. Department of Neuroscience, Maastricht University, 2. Department of Pharmacology and Toxicology, Maastricht University, 3. Department of Urology, Maastricht University Medical Center
Basic Science, Pharmacology, Biomechanics, Animal Study

14:12

#156 The role of capsaicin-sensitive C-fiber afferent pathways in the control of micturition in normal mice and lower urinary tract dysfunction in mice with spinal cord injury

Kadekawa K¹, Yoshiyama M², Wada N³, Shimizu T³, Majima T⁴, Tyagi P³, Kanai A³, de Groat W³, Sugaya K⁵, Yoshimura N³
1. Okinawa Kyodo Hospital, 2. University of Yamanashi, 3. University of Pittsburgh, 4. University of Nagoya, 5. Southern Knight's Laboratory
Spinal Cord Injury, Voiding Dysfunction , Detrusor Overactivity

14:20

#157 TRANSIENT RECEPTOR POTENTIAL MELASTATIN 2 (TRPM2) MEDIATES LIPOPOLYSACCHARIDE (LPS)-INDUCED INFRAMMATORY BLADDER PAIN AND FREQUENT VOIDING IN MICE

Kamei J¹, Aizawa N², Nakagawa T³, Akiyama Y¹, Kaneko S⁴, Homma Y⁵, Igawa Y²
1. Department of Continence Medicine and Urology, The University of Tokyo Graduate School of Medicine, 2. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 3. Department of Pharmacy, Kyoto University Hospital, 4. Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 5. Department of Urology, The University of Tokyo Graduate School of Medicine
Animal Study, Basic Science, Infection, Urinary Tract, Painful Bladder Syndrome/Interstitial Cystitis (IC), Pathophysiology

14:27

#158 Combinational effects of muscarinic receptor inhibition and β3-adrenoceptor simulation on neurogenic bladder dysfunction in rats with spinal cord injury (SCI)

Wada N¹, Shimizu T², Shimizu N², Takai S², Tyagi P², Kakizaki H³, Yoshimura N²
1. The Department of Urology, University of Pittsburgh, The Department of Renal and Urologic Surgery, Asahikawa Medical University, 2. The Department of Urology, University of Pittsburgh, 3. The Department of Renal and Urologic Surgery, Asahikawa Medical University
Spinal Cord Injury, Animal Study, Detrusor Overactivity, Overactive Bladder, Pharmacology

14:35

#159 Nrf2 activation attenuates ischemia-induced detrusor overactivity by downregulating associated endoplasmic reticulum stress, autophagy, and apoptosis in rat bladder

Tai H¹, Yu H¹
1. National Taiwan University Hospital
Animal Study, Detrusor Overactivity, Overactive Bladder

14:42

#160 EFFECTS OF SILODOSIN AND IMIDAFENACIN ON THE BLADDER MECHANOSENSITIVE AFFERENT ACTIVITIES OF A-DELTA- AND C-FIBERS RELATED WITH MICROCONTRACTIONS IN MALE RATS WITH BLADDER OUTLET OBSTRUCTION

Aizawa N¹, Fukuhara H², Fujimura T², Homma Y², Igawa Y¹
1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 2. Department of Urology, The University of Tokyo Graduate School of Medicine
Basic Science, Bladder Outlet Obstruction , Pharmacology, Physiology

14:50

#161 Effects of combination treatment with fesoterodine and mirabegron on urinary bladder functions of pelvic congestion model in rats

Kadekawa K¹, Sugaya K¹, Nishijima S¹, Yamagami H², Hizue M², Ito Y³, Yamada S³
1. Southern Knights' Laboratory, 2. Pfizer Japan Inc., 3. Graduate School of Pharmaceutical Sciences, University of Shizuoka
Animal Study, Overactive Bladder, Pharmacology

14:57

#162 Effects of human amniotic fluid stem cells on chronic bladder-ischemia associated changes in rat bladder function

Liang C¹, Shaw S S¹, Lin Y¹, Lee T¹
1. Chang Gung Memorial Hospital Linkou Medical Center
Animal Study, Detrusor Overactivity, Molecular Biology, Stem Cells / Tissue Engineering

15:05

#163 Differential responsiveness to sacral neurostimulation across the bladder filling cycle in rodents: Later-phase is more effective for increasing bladder capacity than earlier-phase stimulation

Potts B A¹, Degoski D J², Brooks J M², Peterson A C¹, Nelson D E³, Brink T³, Fraser M O⁴
1. Duke University Medical Center, 2. Institute for Medical Research, 3. Medtronic, Inc., 4. Duke University and Durham Veterans Affairs Medical Centers
Neuromodulation, Physiology, Overactive Bladder, Basic Science, Animal Study

15:12

#164 p75 neurotrophin receptor inhibition for treatment of radiation cystitis

Zabbarova I¹, Ikeda Y¹, Kullmann F A¹, Birder L¹, Carder E², Wipf P², Kanai A¹
1. University of Pittsburgh School of Medicine, 2. University of Pittsburgh, Department of Chemistry
Animal Study, Detrusor Overactivity, Pathophysiology

15:20

#165 Protective effect of Allopurinol against ischemia/reperfusion injury in rat urinary bladders

Na Y G¹, Shin J¹, Song K H¹, Lim J S¹, Kim G²
1. Chungnam national university hospital, 2. Korea Basic Science Institute
Voiding Dysfunction , Basic Science, Physiology

15:27

#166 Bladder pain induced in rats by chronic stress is mediated by prolonged stimulation of alpha 1A adrenoceptors.

Charrua A¹, Matos R¹, Serrão P¹, Cruz F¹
1. Faculty of Medicine University of Porto
Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science, Pharmacology