Despite the growing evidence in the field of lower urinary tract symptoms, the development and interpretation of guidelines remains difficult. This workshop aims to provide ICS members (both guideline-developers and users) with important background knowledge to enhance the quality of future guidelines. 
Within the allotted time, we will focus on the following aspects: 
- GRADE methodology and systematic reviews & meta-analyses
 
- What is a risk factor?
 
- Interpretation of odds ratios for common conditions.
 
- Statistical significance vs. clinical relevance for treatment outcomes?
 
- The impact of the setting from which evidence arises
 
 
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