ICS 2017 Scientific Podium Short Oral Session S22

Basic Science 2

Scientific Podium Short Oral Session S22

Speakers
	Thursday 14th September 2017
	14:00 - 15:00
	Spadolini D Capacity: 200
K Karl-Erik Andersson ICS Chair C Chris E Constantinou ICS Chair

Session Schedule

14:00

#458 Effects of tadalafil, a PDE type 5 inhibitor, on the bladder mechanosensitive afferent activities related to microcontractions in male rats with bladder outlet obstruction

Aizawa N¹, Fukuhara H², Fujimura T², Homma Y², Igawa Y¹
1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 2. Department of Urology, The University of Tokyo Graduate School of Medicine
Basic Science, Physiology, Pharmacology, Bladder Outlet Obstruction

14:07

#459 Chronic DPP-4 inhibition improved bladder dysfunction and hemodynamics in rats wih ligation of internal iliac arteries

Hotta Y¹, Takahashi S¹, Tokoro M¹, Kataoka T², Maeda Y¹, Hamakawa T³, Sasaki S³, Yasui T³, Kimura K⁴
1. Department of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2. Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, 3. Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, 4. Department of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University/Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University
Animal Study, Pharmacology, Basic Science, Underactive Bladder, Neuropathies: Peripheral

14:15

#460 Role of β3-adrenoceptors in the control of the urethral continence function in female rats

Kwon J¹, Suzuki T¹, Takaoka E¹, Shimizu N¹, Takai S¹, Shimizu T¹, Cho D², Yoshimura N¹
1. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA, 2. Department of Urology, Cha University School of Medicine, Gumi, South Korea
Animal Study, Female, Pharmacology, Physiology, Basic Science

14:22

#461 Inhibition of purinergic P2X7 receptor activity attenuates apoptosis evoked by radiation bystander effects in bladder urothelial and fibroblast cells

Srivastava K¹, Breen C¹, Bill M¹, McCloskey K¹
1. Queen's University Belfast
Basic Science, Molecular Biology, Pharmacology, Physiology

14:30

#462 Hyperglycemia Enhances Bladder Smooth Muscle Excitability through a Caveolae Dependent Facilitation of Rho-ROCK signaling

Cristofaro V¹, Carew J A¹, Dasari S P¹, Goyal R K¹, Sullivan M P¹
1. Boston VA Healthcare System, Harvard Medical School
Animal Study, Basic Science, Pathophysiology, Detrusor Overactivity

14:37

#463 AGE IS ASSOCIATED WITH AN ALTERED ROLE OF THE HYPERPOLARIZATION ACTIVATED, CYCLIC NUCLEOTIDE GATED (HCN) ION CHANNEL IN ADRENERGIC DETRUSOR RELAXATION
PRIZE AWARD: Best in Category Prize - Pharmacology

Al-Naggar I¹, Hardy C², Taweh O³, Mobley A⁴, Kuchel G¹, Smith P⁵
1. University of Connecticut School of Medicine, Center on Aging, 2. University of Connecticut Graduate School, Neurosciences, 3. University of Connecticut, 4. Western New England University, 5. University of Connecticut School of Medicine Department of Surgery, Center on Aging, CT Institute for Brain and Cognitive Science
Physiology, Molecular Biology, Sensory Dysfunction, Gerontology

14:45

#464 Effect of T-type Calcium Channel Blocker Mibefradil on Cyclophosphamide-induced cystitis in mouse

Lee S J¹, Lee D²
1. Kyunghee University Hospital, 2. Kyunghee University Gangdong Hospital
Detrusor Overactivity, Pharmacology, Pain, Pelvic/Perineal

14:52

#465 Role of nerve growth factor in hyperexcitability of capsaicin sensitive bladder afferent neurons in spinal cord injured mice

Shimizu T¹, Majima T², Suzuki T², Shimizu N², Wada N², Kadekawa K², Takai S², Takaoka E², Kwon J², Tyagi P², Saito M³, Yoshimura N²
1. Department of Pharmacology, Kochi Medical School, Kochi University and Department of Urology, University of Pittsburgh School of Medicine, 2. Department of Urology, University of Pittsburgh School of Medicine, 3. Department of Pharmacology, Kochi Medical School, Kochi University
Animal Study, Basic Science, Detrusor Overactivity, Physiology, Spinal Cord Injury