The Aetiology of Detrusor Underactivity

Kocadag H1, Trimboli M1, Axell R G1, Pakzad M H1, Hamid R1, Ockrim J L1, Greenwell T J1

Research Type

Clinical

Abstract Category

Urodynamics

Abstract 179
Open Discussion ePosters
Scientific Open Discussion Session 7
Wednesday 29th August 2018
12:20 - 12:25 (ePoster Station 12)
Exhibition Hall
Urodynamics Equipment Urodynamics Techniques Underactive Bladder Detrusor Hypocontractility
1. UCLH NHS Foundation Trust
Presenter
R

Rizwan Hamid

Links

Poster

Abstract

Hypothesis / aims of study
Detrusor underactivity (DU) occurs in 9-48% of the population depending on age, sex and definition. We assessed the incidence and possible causes of DU in men and women having a urodynamic assessment at our institution for refractory lower urinary tract symptoms in a 20-month period.
Study design, materials and methods
We reviewed the urodynamic diagnosis and possible aetiology of all 1256 (510 male) patients attending for videourodynamics and simple urodynamics for the above indications between 31/5/16 and 3/1/18. Detrusor underactivity was defined as per 2002 ICS definition. Details on DU patient demographics and past medical and surgical history were determined and are detailed in Table 1. Statistical analysis was by T-Test and Chi Square analysis and significance determine as P < 0.05.
Results
101 (50 male) patients were excluded for trace or test quality issues.  Of the remainder 440 (38%) had DU; 38% (176) of men and 41% (264) of women (Table 1).
Interpretation of results
Neuropathic DU was significantly more common in women. Non-neuropathic women with DU were significantly younger than their male equivalents. Risk factors for non-neuropathic DU include previous SUI, POP or pelvic surgery in women and prior radical prostatectomy in men.
Concluding message
Detrusor underactivity was demonstrated in 38% of our patient population. Neuropathic DU was significantly more common in women. Risk factors for non-neuropathic DU include previous SUI, POP or pelvic surgery in women and prior radical prostatectomy in men.
Figure 1
Disclosures
Funding None Clinical Trial No Subjects Human Ethics not Req'd Retrospective audit of data Helsinki Yes Informed Consent No
15/05/2022 12:20:18