Factors affecting the period between the first and second hydrodistension in females with painful bladder syndrome and interstitial cystitis

Kim H1, Shin D1, Cho W2, Yoon C3, Choi S4, Min K5, Oh T6, Park S1, Lee J1

Research Type

Clinical

Abstract Category

Pelvic Pain Syndromes / Sexual Dysfunction

Abstract 451
Pain Mediators and Interventions
Scientific Podium Short Oral Session 21
Thursday 5th September 2019
15:22 - 15:30
Hall G1
Surgery Painful Bladder Syndrome/Interstitial Cystitis (IC) Female
1.Pusan National University Hospital, 2.Dong-A University Hospital, 3.BHS Han-seo Hospital, 4.Kosin University College of Medicine, 5.Inje University Busan Paik Hospital, 6.Samsung Changwon Hospital
Presenter
D

Dong Gil Shin

Links

Abstract

Hypothesis / aims of study
The present study was aimed to investigate the factors affecting the period between the first and second hydrodistention (HD) in female painful bladder syndrome/interstitial cystitis (PBS/IC) patients.
Study design, materials and methods
Among 52 PBS/IC females who underwent HD, 32 patients who received the second HD due to symptom recurrence were included in the study. Clinical information of the patients such as age, duration suffered from the disease, preoperative functional bladder capacity (FBC), and the distended bladder volume during the first HD were investigated. Also, the period between the first and second HD and the volume difference between preoperative FBC and distended bladder volume during the first HD (ΔVolume_Bladder = Distended bladder volume during the first HD – Preoperative FBC) were calculated for the analysis. All investigated data were statistically analyzed by using simple and multiple linear regression test to find the factors affecting the period between the first and second HD in female PBS/IC patients.
Results
The mean values of age, duration of PBS/IC, preoperative FBC, and the distended bladder volume during the first HD are shown in the Table. The mean period between the first and second hydrodistension and the mean ΔVolume_Bladder was 9.63 ± 9.38 months and 273.50 ± 72.80 mL, respectively. Distended bladder volume during the first HD and ΔVolume_Bladder were the parameters that showed significant correlation with the period between the first and second HD (p = 0.003 and p <0.001, respectively) according to simple linear regression test. In multiple linear regression test, only ΔVolume_Bladder showed significant result with period between the first and second HD (p <0.001).
Interpretation of results
According to simple linear regression test, larger distended bladder volume during the first HD and ΔVolume_Bladder significantly elongated the period between the first and second HD. In multiple linear regression test, ΔVolume_Bladder was the only factor that significantly elongated the period between the first and second HD.
Concluding message
Larger volume difference between preoperative FBC and distended bladder volume during the first HD elongates the symptom-free period of PBS/IC females after receiving HD.
Figure 1
Disclosures
Funding None Clinical Trial Yes Public Registry No RCT No Subjects Human Ethics not Req'd it was a retrospective study based on the medical records. Helsinki Yes Informed Consent Yes