DO UNNOTICED AND CONTINUOUS URINARY INCONTINENCE PATTERNS HAVE DIFFERENT CLINICAL AND/OR URODYNAMIC CHARACTERISTICS?

Gomez De Vicente J1, De Castro Guerin C1, Garcia Matres M1, Jimenez Cidre M2, Lopez Fando L2, Ballesteros C1, Martinez Piñeiro L1

Research Type

Clinical

Abstract Category

Urodynamics

Abstract 545
ePoster 8
Scientific Open Discussion Session 36
On-Demand
Female Incontinence Questionnaire
1. HOSPITAL LA PAZ, 2. HOSPITAL RAMON Y CAJAL
Presenter
J

Jose Miguel Gomez De Vicente

Links

Abstract

Hypothesis / aims of study
In a retrospective review of 395 non-neurogenic women with LUTS (ICIQ-UI SHORT FORM EXTENDED INCONTINENCE PATTERNS CAN PREDICT INCONTINENCE SEVERITY #22146), we found that ICIQ-UI short form questionnaire scores were highest for Mixed Urinary Incontinence (MUI), intermediate for Urgency UI (UUI) and lowest for Stress UI (SUI). But those patients who leaked all the time or for no obvious reason, had significantly higher scores than those who did not. Thus, our objective was to determine if these 6 patterns, that is, non severe SUI (NS-SUI), UUI (NS-UUI), mixed (NS-MUI), severe SUI (S-SUI), UUI (S-UUI) and MUI (S-MUI) have different clinical and/or urodynamic characteristics.
Study design, materials and methods
-We conducted a retrospective review of 395 non-neurogenic women with lower urinary tract symptoms who were studied in a Urodynamic Unit.
-We prospectively collected data from ICIQ-UI short form, 3 day bladder diary (3dBD), stress test, free flowmetry with residual urine, cystometry and pressure-flow study. 
-Patients were classified as SUI if they leaked when sneezing, coughing or with physical activity, UUI if they leaked before getting to the toilet and MUI if they leaked for both reasons. 
-They were further subclassified as severe if they leaked all the time or for no obvious reason, and non severe if they did not. 
-Clinical and urodynamic variables between S and NS patients for every type of UI pattern were compared.
-Continuous variables were compared using Kruskal-Wallis test and chi-square test for frequencies, as variables distribution was not normal.
Results
-69 patients (17.4%) were excluded because they did not have UI; 33 (8.3%) did not fit in any of these patterns: 3 (0.7%) had postmicturition UI, 23 (5.8%) leaked all the time or for no obvious reason without any other UI pattern and 7 (1.2%) did not mark any pattern although they had scored the questionnaire. In total, 293 patients were included for analysis. 
-In Figure 1 we show differences in 3dBD and stress test between severe and non-severe forms of SUI, UUI and MUI. We only found significant differences in 3dBD for number of urgency episodes between S-UUI/NS-UUI (4,3 vs 11,3, p=0,005) and S-MUI/NS-MUI (4,6 vs 5,6, p=0,044), for urgency incontinence episodes between S-UUI/NS-UUI (1,6 vs 11, p<0,001) and S-MUI/NS-MUI (2 vs 3,1, p=0,002), and in number of pads between S-MUI/NS-MUI (1,6 vs 3, p0,005). However, some data was lost because of incomplete 3dBD filling in SUI and UUI patients. 
-In Figure 2, we show differences in free flow and urodynamic variables. Although we found trends in some variables, none of them were significant.
Interpretation of results
Although we found higher ICIQ-UI scores of patients who leaked for no obvious reason or all the time, we could only find differences in some 3dBD variables for S-UUI/NS-UUI and S-MUI/NS-MUI. This study could not demonstrate differences in urodynamic variables.
Concluding message
Although unnoticed and continuous UI are clinically different, they don´t seem to have different urodynamic behavior.
Figure 1 Clinical differences between severe and non-severe UI pattern
Figure 2 Urodynamic differences between severe and non-severe UI pattern
Disclosures
Funding None Clinical Trial No Subjects Human Ethics not Req'd It is a retrospective anonymous study with general conclusions Helsinki Yes Informed Consent No
06/05/2024 02:44:25