Lori A Birder ICS Chair
Georgi Petkov ICS Chair
#366 Is soluble VEGFR1 a putative biomarker and therapeutic target for BPS/IC?
Presenter: Ana Charrua
Ribeiro-Oliveira R1, Mendes P2, Manso M3, Pinto R2, Cruz F2, Charrua A11. I3S and FMUP, 2. FMUP, I3S, CHSJ, 3. CHSJ Painful Bladder Syndrome/Interstitial Cystitis (IC), Female, Basic Science
#367 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONIST AS A NOVEL TREATMENT FOR INTERSTITIAL CYSTITIS: A RAT MODEL
Presenter: Craig Comiter
Comiter C1, Dobberfuhl A1, Mahal A21. Stanford University, 2. University of Nebraska Painful Bladder Syndrome/Interstitial Cystitis (IC), Voiding Dysfunction , Pain, Pelvic/Perineal, Animal Study
#368 Effects of a soluble guanylate cyclase activator, BAY 60-2770, on neurogenic lower urinary tract dysfunction in mice with spinal cord injury
Presenter: Daisuke Gotoh
Gotoh D1, Saito T1, Kurobe M1, Igarashi T1, Singh N1, Miyake M2, Torimoto K2, Fujimoto K2, Yoshimura N11. University of Pittsburgh, 2. Nara Medical University Animal Study, Detrusor Overactivity, Pharmacology, Physiology, Spinal Cord Injury
#369 NERVE GROWTH FACTOR PRECURSOR (PRONGF) EXERTS DIFFERENT BIOLOGICAL ACTIONS ON UROTHELIAL AND SMOOTH MUSCLE CELLS OF RODENTS BLADDERS.
Presenter: Lysanne Campeau
Mossa A1, Cammisotto P2, Campeau L31. McGill University, 2. Lady Davis Institute, 3. Jewish General Hospital, McGill University Basic Science, Cell Culture, Molecular Biology, Pathophysiology, Neuropathies: Peripheral
#370 Inhibiting miR-21-5p alleviates bladder fibrosis and detrusor overactivity in spinal cord injured rats
Presenter: Zhenhua Shang
Shang Z1, Ou T11. Xuanwu Hospital Capital Medical University Spinal Cord Injury, Animal Study, Detrusor Overactivity, Basic Science
#371 Sex differences in bladder wall fibrosis and compliance in spinal cord transected mice—role of angiotensin signalling
Presenter: Irina Zabbarova
Zabbarova I1, Ikeda Y1, Kozlowski M1, Birder L1, Fry C2, Kanai A11. University of Pittsburgh, 2. University of Bristol Spinal Cord Injury, Basic Science, Animal Study
#372 Losartan prevents bladder fibrosis and protects renal function in rats with neurogenic bladder
Presenter: Jian Guo Wen
Wen J1, He Y1, Pu Q1, Wen Y1, Zhai R1, Ma Y1, Liu E1, Xing D1, Ji F1, Yang X11. Pediatric Urodynamic Centre, Department of Urology, the First Affiliated Hospital of Zhengzhou University, China Animal Study, Underactive Bladder, Neuropathies: Central
#373 Urothelial lysosomal dysfunction causes bladder hyperactivity and inflammation
Presenter: Jonathan Beckel
Rodriguez R1, Phipps S1, Obidike C1, Daugherty S1, Beckel J11. University of Pittsburgh, PA USA Painful Bladder Syndrome/Interstitial Cystitis (IC), Molecular Biology, Urgency/Frequency, Voiding Dysfunction , Overactive Bladder
#374 Acid-sensing ion channel 3 (ASIC3) inhibitor increases functional bladder capacity with or without acidic irritation of lower urinary tract in mice when administering intraperitoneally but not intravesically
Presenter: Mitsuharu Yoshiyama
Yoshiyama M1, Kobayashi H2, Araki I3, Takeda M41. Shintotsuka Hospital, 2. Kobayashi Urology Clinic, 3. Koka Office of Public Health and Welfare, 4. University of Yamanashi Basic Science, Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC)
#375 Mast cell tryptase causes lower urinary tract dysfunction associated with chronic ischemia
Presenter: Hidenori Akaihata
Akaihata H1, Yoshida Y1, Imai H1, Meguro S1, Honda R1, Matsuoka K1, Hoshi S1, Hata J1, Sato Y1, Kataoka M1, Ogawa S1, Haga N1, Kojima Y11. Fukushima Medical University Animal Study, Overactive Bladder, Prevention
#376 Long-lasting bladder hypersensitivity with frequent urination induced by intravesical application of of hydrogen peroxide in rats with pelvic venous congestion
Presenter: Takahisa Suzuki
Suzuki T1, Mizoguchi S2, Kurobe M2, Saito T2, Takaoka E2, Kishida T3, Yao M4, Yoshimura N21. University of Pittsburgh, Kanagawa Cancer Center, 2. University of Pittsburgh, 3. Kanagawa Cancer Center, 4. Yokohama City University Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC), Urgency/Frequency, Basic Science
#377 A pilot animal model to identify the intravesical bladder irritant cystometric dose response threshold for six common environmental exposures associated with overactive and painful bladder dysfunction in humans with IC/BPS
Presenter: Chen Shenhar
Shenhar C1, Dobberfuhl A21. Rabin Medical Center, Div. of Urology, 2. Stanford University, Dept. of Urology Animal Study, Basic Science, Painful Bladder Syndrome/Interstitial Cystitis (IC)