NON-ABLATIVE RADIOFREQUENCY IMPROVES HEMODYNAMIC PARAMETERS IN PATIENTS WITH ERECTILE DYSFUNCTION: PRELIMINARY DATA.

Mamede C1, Quibervile A1, Sodré P1, Cerqueira M1, Sodré D1, Teles A1, Canário A1, Marianno A1, Alencar C1, Cantharino C1, Balthazar C1, Jorge D1, Pereira I1, Oliveira I1, Santos J1, Coutinho J1, Piason L1, Zuza M1, Oliveira M1, Freire P1, Gomes T1, Brito V1, Matos R1, Lordelo P1

Research Type

Clinical

Abstract Category

Rehabilitation

Abstract 525
On Demand Rehabilitation
Scientific Open Discussion Session 34
On-Demand
Male Sexual Dysfunction Rehabilitation
1. Patrícia Lordêlo´s Institute (IPL) - Pelvic Floor Care Center (CAAP) - Bahiana School of Medicine and Public Health
Presenter
L

Lucas Piason

Links

Abstract

Hypothesis / aims of study
Radiofrequency can raise penile blood flow, improving hemodynamic parameters enhancing erection quality./ To observe the effect of radiofrequency on hemodynamic parameters in men with erectile dysfunction
Study design, materials and methods
This shows preliminary data from two patients. Inclusion criteria were age between 30 and 80 years and the presence of erectile dysfunction complaints. Exclusion criteria were history of neurological disease, diabetes mellitus, Peyronie's disease, psychiatric diseases, patients with anatomical malformations in the genital region and premature ejaculation. The patients underwent 8 sessions of non-ablative radiofrequency at 41ºC for two minutes using the Ibramed Neartek® equipment. To assess the erection function of patients, the International Index of Erectile Function 5 (IIEF-5) was applied. In addition, hemodynamic data such as systolic velocity peak and end diastolic velocity were collected in the right cavernous artery (RCA) and left cavernous artery (LCA) by doppler ultrasound of the penis.
Results
The patient M.A.O.V. scored 11 before the application of eight sessions of non-ablative radiofrequency, and 25 at the endo f it, in the IIEF-5 questionnaire. He reached an initial systolic velocity peak of 41 cm/s on the RCA, and 37 cm/s on the LCA, before the intervention; and 43 cm/s on the RCA and 35 cm/s on LCA, after the intervention. The end diastolic velocity of this patient reached 15 cm/s on the RCA, and 10 cm/s on the LCA before the intervention; and an end diastolic velocity of 8 cm/s on the RCA and 0 cm/s on the LCA, after the intervention.
The patient M.A.O.V. scored 7 before the intervention and 8 at the end, in the IIEF-5 questionnaire. He reached an initial peak systolic velocity of 31 cm/s on the RCA, and 62 cm/s on the LCA, before the intervention; and 25 cm/s on the RCA, and 61 cm/s on the LCA, after the intervention. Regarding the end diastolic velocity, the same patient reached 10 cm/s on the RCA, and 17 cm/s on the LCA before the intervention; and 0 cm/s on the RCA and 15 cm/s on the LCA, after the intervention.
Interpretation of results
As observed in the results, both patients showed improvement in hemodynamic values  after the application of eight sessions of non-ablative radiofrequency, mainly in the end diastolic velocity, where values below 5 cm/s were reached, considered the cutoff point to exclude the veno-occlusive disease. This suggests that the formation of collagen provided by ionic movement seems to work better in patients who have occlusive venous erectile dysfunction, values confirmed by an increase in the IIEF-5 score.
Concluding message
Radiofrequency treatment suggested an improvement in hemodynamic parameters of the erectile dysfunction, based on the results evidenced in the patients included in the study. Thus, there are few data in the literature on such treatment in cases of erectile dysfunction, requiring a better scientific basis for the adequation of treatment for these patients. Therefore, radiofrequency treatment can be a therapeutic alternative for this population.
Figure 1 Table 1 - Hemodynamic parameters and IIEF-5 in the two research patients.
References
  1. MOBLEY, D. F.; KHERA, M.; BAUM, N. Recents advances in the treatment of erectile dysfuntion. Postgraduate Medical Journal. v.93, n.1101. p.679-685.
  2. PORST, H.; BURNETT, A.; BROCK, G.; GHANEM, H.; GIULIANO, F.; GLINA, S.; HELLSTROM, W.; MARTIN-MORALES, A.; SALONIA, A.; SHARLIP, I.; ISSM Standards Committee for Sexual Medicine. (2013). SOP conservative (medical and mechanical) treatment of erectile dysfunction. Journal of Sexual Medicine. v.10. n.1. 2013, p.130–171.
Disclosures
Funding Ibramed Clinical Trial No Subjects Human Ethics Committee Bahiana School of Medicine and Public Health Helsinki Yes Informed Consent Yes
21/04/2024 21:05:34