Bladder Wall Surface Science; the Relevance of a Entrapped Water Microenvironment. GAG’s, Receptors, Microbiome and Novel Therapeutic Developments

Workshop 7

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Pre-registration for this workshop is required. https://www.ics.org/2021/register

Workshop Schedule

17:00

Scott Glickman

17:05

Dick A.W. Janssen

17:20

Wouter Everaerts

17:35

Sajjad Rahnama'i

17:50

Robert Hurst

18:05

Dick A.W. Janssen
Wouter Everaerts
Sajjad Rahnama'i
Scott Glickman
Robert Hurst

Aims & Objectives

Intermediate
90 minutes
Pharmacology
Pure and Applied Science / Translational
glycosaminoglycans microbiome drug therapy
Urology, Pure and Applied Science

This workshop provides the latest insights in preclinical science on bladder wall surface functions. The aim is to better understand: 1) How glycosaminoglycan-proteoglycan complexes function in the bladder 2) How proteoglycan-GAG complexes could be used as therapy or drug vehicle for intravesical therapy 3) Which urothelial cell membrane receptors respond to intravesical treatment and 4) How benign bacterial flora interact to keep the bladder healthy. We want to get scientists and clinicians together to educate them about the complexities and implications that these structures have on bladder (patho)physiology and show the therapeutic potential of this microenvironment to improve bladder health.

Learning Objectives

  • Learn about the complexities and functions of different GAG’s and proteoglycan-GAG complexes create a water-retaining microenvironment on the bladder wall surface and how GAG’s can be used for intravesical therapies
  • Learn about urothelial cell membrane receptors and their response to local intravesical treatment
  • Learn about the functions of the urogenital microbiome

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