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#506 Androgen receptor localisation in buccal mucosa: can buccal mucosa be used in primary hypospadias surgery in prepubertal boys?
Tsachouridis G1, Viester M1, Kuijt E1, Pikker T1, Den Ouden K2, Van Dam R1, De Kort L1, De Graaf P11. UMCU, Department of Urology, Utrecht, the Netherlands, 2. UMCU, Department of Nephrology, Utrecht, the Netherlands
Basic Science, Pediatrics, Stem Cells / Tissue Engineering
#507 Cellular pathways contributing to fibrosis in the bladder wall of children with exstrophy
Xie B1, Johal N2, Jabr R3, Kanai A4, Ahmed A3, Fry C51. Imperial College London, 2. Great Ormond St Hospital, 3. University College London, 4. University of Pittsburgh, 5. University of Bristol
Basic Science, Pathophysiology, Pediatrics
#508 Downregulation of Cytochrome B5 Reductase 3 in the Mouse Bladder Induces Urinary Frequency
Ikeda Y1, Zabbarova I1, Tyagi P1, Fry C2, Birder L1, Kanai A11. University of Pittsburgh, 2. University of Bristol
Animal Study, Basic Science, Overactive Bladder, Pathophysiology
#509 Low-energy shockwave therapy ameliorates ischemic-induced overactive bladder in a rat model with higher expression of soluble guanylate cyclase and vascular endothelial growth factor.
Kimura S1, Kawamorita N1, Sato T1, Izumi H1, Ito A11. Department of Urology, Tohoku University Graduate School of Medicine
Basic Science, New Devices, Overactive Bladder, Pre-Clinical testing, Urgency/Frequency
#510 Neurite outgrowth agent tas3731 prevents urethra denervation and dysfunction following diabetes mellitus in rats
Akasaka D1, Sakakibara F1, Nakano K1, Demizu S1, Hakozaki A11. Taiho Pharmaceutical Co., Ltd.
Pharmacology, Animal Study, Neuromodulation, Underactive Bladder, Voiding Dysfunction
#511 Age-related changes in lower urinary tract function in rats with altered nitric oxide mechanisms
Gotoh D1, Morizawa Y1, Hori S1, Nakai Y1, Miyake M1, Torimoto K1, Fujimoto K1, Yoshimura N21. Nara Medical University, 2. University of Pittsburgh
Basic Science, Animal Study, Physiology, Voiding Dysfunction , Overactive Bladder
#512 Aging results in reduced sensory innervation of the bladder trigone in rats
De Rijk M1, Peter S1, Wolf-Johnston A2, Van Koeveringe G3, Birder L21. Department of Urology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands, 2. Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh PA 15261 USA, 3. Department of Urology, Maastricht University Medical Center+ (MUMC+), The Netherlands
Animal Study, Basic Science, Biochemistry , Sensory Dysfunction, Gerontology
#513 Mitochondrial-Targeted Free Radical Scavenger, XJB-5-131, Protects the Bladder Against Radiation Cystitis without Affecting Tumour Shrinkage
Ikeda Y1, Zabbarova I1, Wipf P1, Kanai A11. University of Pittsburgh
Animal Study, Basic Science, Pathophysiology, Pharmacology
#514 Rational drug design to identify a new urease inhibitor to treat urinary catheter blockage.
Heylen R1, Cusick N1, Jenkins T11. University of Bath
Biochemistry , Incontinence, Infection, Urinary Tract
#515 Cell Shape Characteristics of Human Skeletal Muscle Cells as a Predictor of Myogenic Competency: A New Paradigm Towards Precision Cell Therapy for Incontinence
Desprez C1, Danovi D2, Knowles C3, Day R11. Centre for Precision Healthcare, UCL Division of Medicine, University College London, Gower Street, London, United Kingdom, 2. Centre for Stem Cells and Regenerative Medicine, King's College London, London, United Kingdom, 3. National Bowel Research Centre and GI Physiology Unit, Blizard Institute, Centre for Neuroscience, Surgery & Trauma, Queen Mary University of London, London, United Kingdom
Anal Incontinence, Basic Science, Pre-Clinical testing, Stem Cells / Tissue Engineering
#516 Functional connectivity analysis in healthy men and women utilizing 7 Tesla MRI during full and empty bladder states
Best in Category Prize: Neurourology
Choksi D1, Schott B1, Karmonik C2, Tran K1, Salazar B3, Boone T3, Khavari R31. Texas A&M College of Medicine, ENMED Program, Houston, TX, 2. Translational Imaging Center, Houston Methodist Research Institute, Houston TX, 3. Department of Urology, Houston Methodist Hospital, Houston TX
Clinical Trial, Imaging, Male, Female
#517 In vitro: Gene expression of GAG synthesizing genes in relation to GAG-therapy.
Van Ginkel C1, Baars C1, Martens F1, Heesakkers J2, Janssen D11. Radboudumc, 2. MUMC+
Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science, Cell Culture, Pathophysiology