Summary by Stefano Palea
Future drugs for the treatment of lower urinary tact symptoms will be probably based on the modulation of sensory pathways. In this context, this session highlighted some new potential targets, i.e. receptors for Transient Receptor Potential family as well as subtypes of Potassium channels.
Of remarkable interest two posters showed the effects, on both cystometric parameters and bladder afferent activities, of a potent Kv7 channel activator (poster 29) and a selective TRPM8 antagonist (poster 30). Finally, a poster described an innovative and relatively cheap technique to measure brain activity during cystometry in anesthetized rats (poster 36).