Retrograde leak point pressure does not predict outcomes following male sling insertion

Toia B1, Jeth J1, Ecclestone H1, Pakzad M H1, Hamid R1, Greenwell T J1, Ockrim J L1

Research Type

Clinical

Abstract Category

Urodynamics

Abstract 184
Open Discussion ePosters
Scientific Open Discussion Session 7
Wednesday 29th August 2018
12:45 - 12:50 (ePoster Station 12)
Exhibition Hall
Male Stress Urinary Incontinence Urodynamics Techniques Incontinence
1. University College London Hospitals
Presenter
R

Rizwan Hamid

Links

Poster

Abstract

Hypothesis / aims of study
It has previously been identified that the only pre-operative predictor of success of male sling is pre-operative pad weight. Retrograde leak point pressure measurement (RLPP) is a urodynamic parameter that provides an objective measurement of external urethral sphincter’s closure pressure. RLLP has the advantage of being reproducible and simple to perform, and has previously been correlated to pad weight. Therefore, we aimed to assess whether RLPP is independently predictive of male sling success.
Study design, materials and methods
Retrospective evaluation of 36 men, mean age 66 who underwent male sling for post prostatectomy incontinence (PPI) between 2012-2017. All patients had RLPP measured prior to surgery using standardized technique. Differences in RLPP for patients who were cured versus those that remained wet was analyzed using Student T-test with a p value <0.05 being significant.
Results
Mean follow up is 28.5 months (range 5- 66). In 29/36 patients incontinence was cured (0 or 1 security pads/day) following male sling insertion (81%), and 7/36 (19%) remained wet. Four patients had temporary post-operative urinary retention, all of whom were in the dry group. Mean preoperative pad weight in the group who remained wet was 943g (range 14-3000), the mean pad weight in the cured group was 182g (range 20-586). Mean RLPP for those cured was 50 cmH20 (range 22-100), for those who remained wet mean RLPP was 35 cmH2O (range 13-63), p=0.53 (Figure 1).
Interpretation of results
Pad weight remains a strong predictor of success of male sling in this cohort. Whilst the trend was suggestive, RLPP did not reach statistical significance to independently predict male sling outcome.
Concluding message
More data is required to develop pad weight and RLPP thresholds and predictive nomograms for PPI surgery
Figure 1
References
  1. Comiter C V, Sullivan MP, Yalla S V (2003) Correlation among maximal urethral closure pressure, retrograde leak point pressure, and abdominal leak point pressure in men with postprostatectomy stress incontinence. Urology 62:75–8
Disclosures
Funding No funding required Clinical Trial No Subjects Human Ethics not Req'd Not required; this was a retrospective review of case notes Helsinki Yes Informed Consent Yes
22/04/2024 19:31:55