Overactive bladder syndrome (OAB) has great negative impact on health related quality of life. In literatures, few studies reported the comparisons of health related quality of life between OAB-wet and OAB-dry female patients. Thus, our aim is to compare the clinical variables and health related quality of life between OAB-wet and OAB-dry women.

Between July 2009 and January 2018, all women with OAB visiting a medical center for evaluation were reviewed. The classification of OAB-wet or OAB-dry is based on the record of three-day bladder diary of each patient. The diagnosis of OAB in each patient was based on the presence of at least one episode of urgency in her three-day bladder diary and with absence of stress urinary incontinence. The presence of at least one episode of urgency associated incontinence was defined to be OAB-wet, otherwise, OAB-dry.  Besides, only female OAB patients with available King’s Health Questionnaire (KHQ) data were reviewed in this study.

A total of 905 OAB women with available KHQ data were reviewed, including 172 (19.0%) OAB-wet and 733 (81.0%) OAB-dry women were included in this study. 
         The mean age and parity is higher in the OAB-wet group, compared with OAB-dry. Women with OAB-wet had higher scores of Overactive Bladder Symptoms Scores (OABSS) and Urgency Severity Scales (USS), as well as urgency, urgency incontinence and severity measures scores, compared with OAB-dry (Table 1). 
        Besides, women with OAB-wet also had higher scores of stress incontinence, nocturnal enuresis and lower scores of voiding difficulty and personal relationships (Table 1).

OAB-wet seems to be a severe form of OAB with the finding of higher severity of OABSS, USS, urgency and urgency incontinence. Despite less negative impact on personal relationships, women with OAB-wet had a poorer quality of life, especially for severity measures, compared with OAB-dry. Besides, OAB-wet women had a higher severity of nocturnal enuresis and stress incontinence, despite less voiding difficulty.

Women with OAB-wet have a poorer health related quality of life, especially in the domain of severity measures. In addition, women with OAB-wet have higher severity of nocturnal enuresis and stress incontinence, despite less voiding difficulty.