A total of 112 women were reviewed in the study.The average Q-tip angle was 41.8 degrees. Based on the receiver operating characteristic curve (ROC) analysis, the optimum cut-off value of the Q-tip angle was ≥ 32 degrees to predict urodynamic stress incontinence (USI) and was determined with the area under the ROC curve being 0.74 (95% confidence interval [CI] = 0.63 to 0.84; sensitivity = 81.8%, specificity = 65.7%, Fig 1).
Age, point Aa, point Ba, point C, USI, detrusor overactivity, pad weight, maximum flow rate, voided volume, functional profile length and pressure transmission ratio (PTR) at maximum urethral pressure (MUP) were significantly correlated with the Q-tip angle.
Multivariable linear regression analysis revealed that point Aa (a, coefficient = 4.8), urodynamic stress incontinence (USI, b, coefficient = 11.7), detrusor overactivity (c, coefficient = -11.3), maximum flow rate (d, coefficient = 0.13) and PTR at MUP (e, coefficient = -0.16) were independent predictors of the Q-tip angle with a constant of 53.8. The predicted Q-tip angle can be denoted by Q-tip angle = 53.8 + 4.8 x a + 11.7 x b – 11.3 x c + 0.13 x d - 0.16 x e.
PTR at MUP (rho = -0.41, Fig 2) had a higher correlation with the Q-tip angle compared with point Aa (rho = 0.38), USI (rho = 0.38), detrusor overactivity (rho = -0.29) and maximum flow rate (rho = 0.26).
PTR at MUP was different between USI and non-USI women. Based on the ROC analysis, the optimum cut-off values of PTR at MUP < 81% to predict USI was determined with the area under the ROC curve being 0.74 (95% CI = 0.64 to 0.83; sensitivity = 85.7%, specificity = 54.9%).
If performing univariate regression analysis with the Q-tip angle, the coefficient of PTR at MUP was -0.18 (95% CI = -0.27 to -0.08, p < 0.001) with a constant of 56.7 (95% CI = 48.1 to 65.4, p < 0.001). Thus, the predicted Q-tip angle for a given PTR at MUP (%, a) could be denoted by Q-tip angle = 56.7 - 0.18 x a. R2 was 0.12.
In addition, a significant correlation between PTR at MUP (< 81 vs. ≥ 81%) and the Q-tip angle (≥ 30 vs. < 30 degrees) was found (rho = -0.29, p = 0.003). Based on the ROC analysis to predict USI, the optimum cut-off value of PTR at MUP < 81% was determined with the ROC area of 0.74.