Intermittent catheterizations in patients with dementia. Correlations of complications with the disease stage.

Samarinas M1, Konstantinidis C2, Moschidis I1, Bousdroukis N1, Kalogiannis D1, Skriapas K1

Research Type

Clinical

Abstract Category

Geriatrics / Gerontology

Abstract 405
E-Poster 2
Scientific Open Discussion ePoster Session 18
Thursday 5th September 2019
13:05 - 13:10 (ePoster Station 12)
Exhibition Hall
Gerontology Voiding Dysfunction Conservative Treatment Infection, Urinary Tract Quality of Life (QoL)
1.General Hospital of Larissa, 2.National Rehabilitation Center, Ilion, Athens, Greece
Presenter
M

Michael Samarinas

Links

Poster

Abstract

Hypothesis / aims of study
Dementia is one of the most common diseases in the elderly. Usually, refers to the reduction of cognitive function leading even to a total inability with the basic everyday activities. A common consequence for dementia patients are voiding symptoms while some of them are for need of intermittent catheterizations due to their substantial post void residuals. The aim of our study is to determine which is the most appropriate provision of safe care for these patients, in order to have the minimum of complications when catheterization is an appropriate therapy.
Study design, materials and methods
This is an observational study over the complications of intermittent catheterizations (IC) in patients with dementia, in relation with the disease stage. The inclusion criteria included all patients referring to our center from December 2016 to December 2018 with a diagnosed dementia type and in any stage of the disease. This group of patients was examined with non-invasive urodynamic test, including frequency volume chart, bladder ultrasound and uroflowmetry and according to the findings were advised for therapy. Patients with a post void residual (PVR) over 150ml, without a clear bladder outlet obstruction and non-eligible for invasive treatment were counseled for IC, either self-catheterization or by their caregivers. Dementia stage has been evaluated according to the Global Deterioration Scale (GDS), which determines their ability of independence in everyday activities. GDS consists of seven levels of independence; the level 1 refers to patients subjectively and objectively normal and fully independent, while level 7 refers to patients with severe dementia, needing complex care. Patients of levels 1-3 are usually totally independent and those of levels 4-7 are in need of caregiving, with the necessity of care setting to increase with the dementia stage. Eligible individuals were under surveillance for six months, focusing on their compliance with the treatment and IC complications, such as urinary tract infections (UTIs), hematuria and hospitalization. The collected data were statistically analyzed with SPSS v23.0, following the Wilcoxon test for non-parametric samples.
Results
Overall 73 patients with dementia visited our center in the predefined period and finally 36 of them (mean age: 74.73 years, range: 71-77) were eligible for our study. The mean PVR was 255.5ml. The 94.4% (34 patients) of them were diagnosed with Alzheimer disease and only 2 patients had a Lewy Bodies dementia. More specifically, they were 24 men with a mean age of 73.75 years (range: 71-77) and mean PVR: 295.5ml and 12 women with a mean age of 75.71 years (range: 72-77) and mean PVR: 215.5ml. Regarding GDS classification, 20 of patients (55.6%) were at levels 1-3 and all of them were self-catheterized, while the rest 16 (44.4%) were at levels 4-7 being catheterized by their caregivers. Among the more independent patients, there were 14 men (70%) and 6 women (30%), while in patients with more advanced disease, there were 10 men (62.5%) and 6 women (37.5%). During the follow-up period, only one male patient in GDS level 7 abandoned treatment with IC, remaining with a permanent catheter. Among the rest 35, there were 5 cases of uncomplicated UTIs (4 in self-catheterized and 1 in dependent-catheterized patients, 3 in men and 2 in women). Furthermore, there were 16 cases of minor hematuria, all in male patients, 11 in self-catheterized and 5 in dependent-catheterized ones. None of the patients needed hospitalization. Comparing patients with a low GDS to those with a higher score, there is a statistically significant difference in the era of UTIs and hematuria, in favor of care-giving catheterization (p= 0.01 and p= 0,006 respectively).
Interpretation of results
The pre-mentioned findings indicate that patients with dementia experience difficulties in self-catheterization, although some of them seem to be fully independent and mostly equally capable with the general population. Considering that care-giving is absolutely necessary for patients with more disabilities, seems that the level of educated care-givers is of high importance.
Concluding message
Intermittent catheterization is a safe treatment option in dementia patients with high PVR, even in those with a high GDS. Interestingly, catheterization by care-givers seems to be safer than self-catheterization even in more independent patients.
References
  1. verbeck MA, Altaweel W, Manu-Marin A, Madersbacher H. Management of LUTS in patients with dementia and associated disorders?. Neurourol Urodyn. 2017 Feb;36(2):245-252. doi: 10.1002/nau.22928. Epub 2015 Nov 20. Review. PubMed PMID: 26588796.
  2. Ganz DA, Koretz BK, Bail JK, McCreath HE, Wenger NS, Roth CP, Reuben DB. Nurse practitioner comanagement for patients in an academic geriatric practice. Am J Manag Care. 2010 Dec 1;16(12):e343-55. PubMed PMID: 21291291; PubMed Central PMCID: PMC3652524.
  3. Schultz-Lampel D. [Bladder disorders in dementia and Alzheimer's disease. Rational diagnostic and therapeutic options]. Urologe A. 2003 Dec;42(12):1579-87. Review. German. PubMed PMID: 14668985.
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee Scientific Council of General Hospital of Larissa Helsinki Yes Informed Consent Yes