A survey of OAB in Chinese junior university students of female and its influence on psychology

Liang Y1, Wen J1, Hu H2, Zhang Z3, Dou Q1, Song C1, Lu C2

Research Type

Clinical

Abstract Category

Overactive Bladder

Abstract 55
OAB: Neuromodulation and Unusual Associations
Scientific Podium Short Oral Session 5
Thursday 19th November 2020
12:07 - 12:15
Pavilion 9
Female Overactive Bladder Infection, Urinary Tract Constipation Urgency Urinary Incontinence
1. First Affiliated Hospital of Xinxiang Medical University, 2. Xinxiang Medical University, 3. Third Affiliated Hospital of Xinxiang Medical University
Presenter
Y

Yu Liang

Links

Abstract

Hypothesis / aims of study
To investigate the prevalence and related risk factors of overactive bladder disease (OAB) in Chinese junior university students of female, and to evaluate the effect of OAB on their psychology.
Study design, materials and methods
From September 2019 to January 2020, 14160 22-year-old female junior university students from 2 universities in China were selected and investigated on the epidemiology of OAB by anonymous questionnaire. The questionnaire included basic information, history of urinary tract infection (UTI), lower urinary tract symptoms (LUTS), intestinal symptoms, OAB symptom score (OABSS), Depression scale and Pittsburgh sleep scale. OAB is defined as urinary urgency with or without urgent urinary incontinence, usually with increased frequency of urine and nocturnal urine, but without urinary tract infections or other exact lesions. The diagnostic criteria of OAB were that the urination urgency score of OABSS was ≥ 2, and the total score was ≥ 3, Dry OAB referred to OAB without urgency incontinence (urgency incontinence score of OABSS=0); wet OAB referred to OAB with urgency incontinence (the urgency incontinence score of OABSS≥1. In addition, the relationships between OAB and sex, age, residence, body mass index (BMI), intestinal symptoms, UTI, menstrual regularity and nocturnal enuresis (NE) were evaluated.
Results
A total of 12701 subjects (age 19 ± 1.0 years) were qualified for statistical analysis. The overall prevalence of OAB was 6.1% (770/12701) in junior university students, the prevalence of dry OAB was 3.8% (478/12701) and wet OAB was 2.3% (292/12701). The prevalence of OAB was related to BMI, NE, constipation, history of UTI and irregular menstruation (P < 0.05), but not with residence and age (P > 0.05). The depression score of OAB group was higher than that of normal group, and OAB seriously affected the sleep quality of patients.
Interpretation of results
The prevalence of OAB in this study is lower than that in other countries, which might be due to differences in OAB definitions, study populations and survey methods. The prevalence of wet OAB is lower than that of female aged 20-29 years old in another study (3.9%), [1]which may be related to the age difference of the investigated population, and the subjects in the current study have a high level of knowledge and a high rate of correct response to the questionnaire. OAB patients frequently use toilets and are afraid to participate in social activities because of urgent and frequent urination, which leads to a series of psychological changes such as inferiority, shame and so on, which seriously affects the mental health of patients.
Concluding message
OAB in junior university students of female is common and significant affects the mental health of patients. Obesity, NE, constipation, UTI and irregular menstruation are the risk factors of OAB.
References
  1. Zhang W, Song Y, He X, et al. Prevalence and risk factors of overactive bladder syndrome in Fuzhou Chinese women[J]. Neurourol Urodyn, 2006, 25(7): 717-721.
Disclosures
Funding Henan Province Medical Science Provincial-ministerial Co-construction Project (No: SBGJ2018059), Natural Science Foundation of China (NSFC) (No. 81670689) and Natural Science Foundation of China (NSFC) (No. U1904208). Clinical Trial No Subjects Human Ethics Committee Xinxiang Medical University Ethics Committee Helsinki Yes Informed Consent Yes