URODYNAMIC AND CLINICAL FEATURES IN WOMEN WITH DYSFUNCTIONAL VOIDING

Mangita A1, Diamantis G2, Konstantinidis C3

Research Type

Clinical

Abstract Category

Female Lower Urinary Tract Symptoms (LUTS) / Voiding Dysfunction

Abstract 200
On Demand Female Lower Urinary Tract Symptoms (LUTS) / Voiding Dysfunction
Scientific Open Discussion Session 17
On-Demand
Female Retrospective Study Voiding Dysfunction
1. Directorate of Nursing Service MSc, PhD, Mutual Health Fund of National Bank of Greece Personnel, 2. . Urologist-Urology and Neuro-urology Unit-National Rehabilitation Center, Athens, Greece, 3. Head of Urology and Neuro-urology Unit- National Rehabilitation Center, Athens, Greece
Presenter
G

Georgios Diamantis

Links

Abstract

Hypothesis / aims of study
Dysfunctional voiding (DV) is characterized by an intermittent and/or fluctuating flow rate due to involuntary intermittent contractions of the peri-urethral striated or levator muscles during voiding in neurologically and anatomic normal women. This study investigated the clinical presentations and UD characteristics in female dysfunctional voiding.
Study design, materials and methods
: A total of 230 women with lower urinary tract symptoms (LUTS) were investigated with urodynamic studies (UDS) from 2012 to 2020.The clinical urinary symptoms and UD characteristics were analyzed. Antimuscarinic or alpha-blocker treatment according to the main complaint of storage or voiding LUTS was respectively given including clean intermittent catheterization.1
Results
There were 16 women diagnosed with DV. Detrusor overactivity (DO)occurred in 63% of women with DV. Patients with DV had low cystometric bladder capacity, high detrusor pressure, low maximum flow rate and large post-void residual volume. A total of 8 patients had storage symptoms,4 had painful symptoms and 14 had voiding symptoms as their chief complaints among those with DV. Among them, difficult urination was the most common chief complaint, followed by urgency and urgency incontinence.
Interpretation of results
Our study showed high incidence of urodynamic DO (63%), small CBC,low Qmax,large postvoid residual volume and high Pdet in patients with DV. 
In our analysis, most women with DV presented with difficult urination as their main symptom. Urgency was also an associated symptom.
In our study, women with BOO complain of not only voiding symptoms but also storage symptoms. In that respect, UDS can provide essential information for differentiation of BOO from overactive bladder (OAB). Additionally, women with underactive bladder (UAV) usually have a high PVR  and  complain of  voiding symptoms. However, some of them have storage symptoms as the chief complaint. Without UDS  ,   an exact  diagnosis  cannot  be  made  in  this  situation.
Although uroflowmetry and residual volume are sometimes useful screening tools for voiding dysfunction, UDS is necessary for distinguishing the DV and providing the appropriate treatment.2
 The present study has some limitations. The first is its retrospective nature and the lack of a control group. In practice, conducting UDSs for normal subjects is difficult, thus we could not compare the UDS of control. Further, although we used a cut-off value for the UDS-based diagnosis of DV, there is a lack of established urodynamic criteria for the diagnosis of DV at present. In addition, we did not investigate the natural history or response to treatment in DV because of the retrospective characteristic of the study.
Concluding message
LUTS voiding symptoms and UD study features of BOO were present in most women with DV.UDS may be necessary for accurate diagnosis in women with voiding symptoms.
References
  1. Kuo HC. Videourodynamic analysis of pathophysiology of men with both storage and voiding lower urinary tract symptoms. Urology. 2007; 70:272–276.
  2. Carlson KV, Rome S, Nitti VW. Dysfunctional voiding in women. J Urol. 2001; 165:143–147, discussion 147–148.
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee National Rehabilitation Center of Greece Helsinki Yes Informed Consent Yes
18/05/2024 23:13:31