Oral mucosa grafting for reconstruction of severe vulvar stenosis due to lichen sclerosus

Alonso Mediavilla E1, Campos-Juanatey F1, Zubillaga Guerrero S1, Muñoz Menendez A2, Mora Ruiz-Moyano R2, Andres Hernandez V2, Varea Malo R1, Fernandez Guzman E1, Garcia Formoso N1, Garcia Herrero J1, Sanchez Gil M1, Ballestero Diego R1, Calleja Hermosa P1, Dominguez Esteban M1, Jubete Castañeda M2, Gutierrez Baños J1

Research Type

Clinical

Abstract Category

Pelvic Pain Syndromes

Abstract 572
On Demand Videos
Scientific Open Discussion Video Session 38
On-Demand
Genital Reconstruction Grafts: Biological Female Sexual Dysfunction
1. Department of Urology - Marques de Valdecilla University Hospital (Santander, Spain), 2. Department of Obstetrics and Gynecology - Marques de Valdecilla University Hospital (Santander, Spain)
Presenter
E

Eneko Alonso Mediavilla

Links

Abstract

Introduction
Vulvar lichen sclerosus is a chronic disease with a great impact on quality of life, causing voiding and sexual symptoms. In severe cases, refractory to topical treatments and interval dilatation, a definitive surgical treatment could be offered. Oral mucosa has previously demonstrated good outcomes against lichen sclerosus in male urethral surgery. We propose vulvar reconstruction using oral mucosa grafts as anovel intervention with promising results.
Design
We present by video the usefulness of the oral mucosa graft for the surgical reconstruction of severe vulvar stenosis due to lichen sclerosus. We show the surgical intervention step by step.  Subsequently, we expose our experience in 3 cases of our series with intermediate-term follow-up.
Results
Initially, we perform the opening of fused labia minora, with sharp excision of affected tissue until the preserved vaginal cavity is fully exposed. After measuring the mucosal defects in both labia minora, we perform oral mucosa harvesting from both inner cheeks. Donor sites are closed using interrupted sutures. We demonstrate the graft placement over labia minora de-epithelialized areas using absorbable material, and postoperative dressing for graft care. Finally we expose the clinical cases of 3 patients of our series, showing preoperative appearance, aspect after surgical intervention and one-year postoperative clinical outcomes.
Conclusion
Labia minora grafting using oral mucosa would prevent lichen sclerosus recurrences, maintaining the patency of vulvar introitus. After 1 year follow-up our results are encouraging, with no need for any re-intervention or dilatation.
Disclosures
Funding There are no financial conflicts of interest to disclose Clinical Trial No Subjects None
15/05/2024 17:34:31