Novel surgical technique for the treatment of total incontinence ‎post-radical cystectomy, a preliminary report

Wadie B1

Research Type

Clinical

Abstract Category

Male Stress Urinary Incontinence (Post Prostatectomy Incontinence)

Abstract 304
Open Discussion ePosters
Scientific Open Discussion Session 22
Friday 9th September 2022
13:10 - 13:15 (ePoster Station 1)
Exhibition Hall
Incontinence Surgery Male
1. Urology and Nephrology Center, Mansoura University
In-Person
Presenter
B

Bassem S Wadie

Links

Poster

Abstract

Hypothesis / aims of study
Radical cystectomy and orthotopic diversion is the surgical treatment of ‎choice in men with muscle-invasive bladder cancer. Sphincter-deficiency ‎incontinence is a drastic consequence. While not life-threatening, it could ‎have a significantly negative impact on a patient’s quality of life. The ‎treatment of such complications is daunting. ‎In a study by Steers W. D 1 including 2238 patients with various forms of ‎the orthotopic neobladder, daytime incontinence was reported to be an ‎average of 13% of patients ‎. In another study 2 based on a mailed ‎questionnaire, 139 of 179 responders used pads at least sometimes; half of ‎them used pads day and night.‎ This trial entails the application ‎of a highly customizable perineal sling in the treatment of post-cystectomy ‎incontinence
Study design, materials and methods
Men after Radical cystectomy and orthotopic diversion (RCOD) with significant daytime incontinence (defined as the use of 5 pads more at least or wearing an external collecting ‎device during daytime) ‎were included. ‎MRI, basic laboratory testing, and a 1-hour pad test were requested. Tailored ‎to the size of the patient’s bulb, Polypropylene mesh is prepared and fixed ‎by 4 No 1. Ethilon sutures were fixed to the inferior pubic ramus on both sides. ‎The tightening of the sling was carried out under a cough test. ‎
Results
‎10 patients have completed 6 months follow-up. The patients’ mean age was 66 ‎years. (56-80 years). Two of these patients had nerve-sparing cystectomy. ‎No evidence of local recurrence on abdominal-pelvic MRI prior to sling. ‎Mean BMI was 25.62 (range: 22-32.4) Mean pad weight gain was 112.5 ‎gm. (80-200). 6 months after surgery, the pad test was negative in 5 patients ‎‎(50%) and positive in 5. The mean increase of pad weight was 14.1 gm. (range ‎‎1-80 gm.). Mean PVR was 17.1 ml (range: 1-82). Average pad use was 2 ‎pads /day (1-3). ‎
Interpretation of results
We utilized Polypropylene as well, being a non-absorbable material that is ‎commonly used in different male slings. Our technique is customizable as it ‎was noted that the size of the bulbospongiosus muscles varies from one to ‎another 3‎ ‎. Hence, the importance of the sling being “tailored: to the proper ‎size of the muscle of every particular patient. Using direct fixation of the ‎sling using 5/8 circle robust needle of Ethilon 1 suture; with direct bite into ‎the inferior pubic ramus cortex with the help of a curved strong needle ‎holder is more time and money-saving than the bone screws and their ‎special drill. ‎
Concluding message
In the short term and based on a small sample, the customized perineal sling ‎described is a safe, easy-to-learn, and effective mode of treatment of post- ‎cystectomy incontinence.‎
Figure 1 The sling is being adjusted to cover the bulbar urethra within its muscle ‎coverings
Figure 2 The sling is being tightened while the patient is asked to cough with his ‎bladder filled with 200 ml of saline. ‎
References
  1. Steers WD.: Voiding dysfunction in the orthotopic neobladder. World J ?Urol. 2000; 18(5):330.?
  2. Ahmadi H, Skinner EC, Simma-Chiang V, et al. Urinary functional ?outcome following radical cystoprostatectomy and ileal neobladder ?reconstruction in male patients. J Urol. 2013; 189 (5):1782.?
  3. Peikert K, Platzek I, Bessède T et al: The male bulbospongiosus muscle ?and its relation to the external anal sphincter. J Urol. 2015; 193(4):1433.?
Disclosures
Funding Institutional Clinical Trial No Subjects Human Ethics not Req'd It is part of the routine work of the voiding dysfunction unit Helsinki Yes Informed Consent Yes
30/04/2024 17:01:52