Does Nocturia Single Question predict moderate and severe male LUTS?

Silva C1, Souza J2, Bellucci C3, Miranda E4, Prezotti J5, Alvaia M3, Bastos Netto J6, Souza Junior A7, Fornari A8, Martins M3, Tiraboschi R3, Gomes C9, Bessa Junior J3

Research Type

Clinical

Abstract Category

Male Lower Urinary Tract Symptoms (LUTS) / Voiding Dysfunction

Abstract 87
Open Discussion ePosters
Scientific Open Discussion Session 7
Thursday 8th September 2022
13:25 - 13:30 (ePoster Station 1)
Exhibition Hall
Male Nocturia Questionnaire
1. Department of Public Health,, 2. Division of Urology, Medical School, University of Sao Paulo, Sao Paulo, Brazil, 3. Division of Urology, Medical School, State University of Feira de Santana, Bahia, Brazil, 4. Division of Urology, Medical School, Federal University of Ceara, Ceara, Brazil, 5. Divisão de Urologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP Brasil, 6. Division of Urology, Medical School, Federal University of Juiz de Fora, Minas Gerais, Brazil, 7. Division of Urology, Western Parana State University, Parana, Brazil, 8. Division of Urology, Federal University of Health Sciences of Porto Alegre, Rio Grande do Sul, Brazilo Alegre, 9. Division of Urology, Medical School, State University of Sao Paulo, Sao Paulo, Brazil
Unconfirmed Presentation Method
Presenter
C

Caroline Santos Silva
Department of Public Health,
Links

Abstract

Hypothesis / aims of study 
Background: Recently, it has been demonstrated that a single-question assessment of nocturia might be a useful alternative to the IPSS.Single-question questionnaires provide a brief and easily administrated tool for the detection of diseases and have been recommended as a screening tool for different specific medical conditions. Objectives: To evaluate the accuracy of a single question on nocturia to identify men with moderate and severe LUTS.
Study design, materials and methods 
Methods:  We evaluated men aged ≥40 years who presented for medical evaluation at two different urological centers. They completed the IPSS and the Nocturia Single Question Scale (NSQS). NSQS consists of a single question assessing nocturia frequency ranging from 0 to 4.  The severity of LUTS using NSQS (index test) versus IPSS (reference standard) was assessed according to the recommendations of the Standards for Reporting of Diagnostic Accuracy Initiative.
Results 
A total of 697 (91.4%) men were included in the analyses. Median age was 60.0 [54.0-68.0] years. Median IPSS and of NSQS episodes were 9.0 [5-17] and 2.0 [1-3], respectively. According to the IPSS, patients presented mild, moderate, and severe symptoms in 262 (37.6%), 279 (40.0%), and 129 (18.6%), respectively. Twenty-seven (3.8%) were asymptomatic.
The NSQS was zero in 118 (17%), one in 141 (20%), two in 197(28%), three in 144(21%), and four or more in 95 subjects (13%). The NSQS was higher in subjects with moderate/severe LUTS than in asymptomatic and with mild symptoms (p<0.001) . The accuracy of the NSQS to discriminate patients with severe LUTS based on the ROC curve was 75% (CI 95% 73 – 82%; p<0.001).
Interpretation of results 
Although the IPSS is the most recommended tool for the assessment of LUTS severity in BPH patients, its use is potentially limited by its length, which could be a burden to patients that would have to read, understand and answer all the questions. Efforts have been applied to create simplified methods capable of evaluating LUTS in adult men.The current study has demonstrated that the NSQS is an accurate tool to predict LUTS severity in adult men without being a time-consuming process to responders and researchers.
Concluding message 
The NSQS may be used as a screening tool to predict the severity of LUTS in men. Patients with none or one void/night have a low probability of severe LUTS, while those with three or more voids have a high probability of moderate or severe symptoms. NSQS can be used as a quick and less expensive alternative in daily clinical practice that could be implemented in the primary care setting.
Figure 1
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee State University of Feira de Santana Ethics Committee Helsinki Yes Informed Consent Yes
08/05/2025 19:27:09