Study design, materials and methods
From January 2015 to January 2019, 72 male patients from Peking University People ’s hospital who underwent TURP treatment were retrospectively analyzed. The age of all patients range from 51 to 89, with an average age of 72 years old. All patients underwent urodynamic examination before surgery. The patients were divided into three groups according to BCI and PdetQmax . DU group(BCI < 100 and PdetQmax ≤40 cmH2O) consisted of 31 patients. Then DU patients were divided into two groups according to the PdetQmax :Group A, PdetQmax ≤20 cmH2O, involving 9 patients; Group B, 20cmH2O < PdetQmax ≤40 cmH2O , involving 22 patients. Non-DU group(BCI≥100 and 40 < PdetQmax ≤60 cmH2O), also named the control GroupC, included 41 patients. There was no statistically significant difference in term of age and duration of disease among the three groups (P < 0 . 05). Preoperative international prostate symptom scores(IPSS)of the three groups were(26.40 ±5.54) , (21.04 ±4.61) and( 18.53 ±4.41), respectively. The quality of life score (QOL) were(4.70 ±1.34), (3.37 ±1.11) and(3.49±1.34), respectively. The Q max were(4.60±2.63), (8.48±2.47) and(11.38±4.00) ml/s, respectively. The residual urine volume (PVR) were(152.90±75.26), (90.78 ±51.97) and(53.23±38.98) ml, respectively. The preoperative IPSS and QOL of patients in group A were significantly higher than those in group B and group C, and the difference was statistically significant (P < 0.05), whereas the difference between group B and group C was not statistically significant (P > 0.05). The preoperative Q max of group A was significantly inferior than that of group B and C, with statistically significant difference (P< 0.05) and group B was significantly inferior than group C, with statistically significant difference (P <0.05). The preoperative PVR of group A was significantly higher than that of group B and group C, with statistically significant difference (P<0.05) and group B was significantly higher than group C, with statistically significant difference (P < 0.05). The above indicators were followed up to compare the improvement for the three groups of patient. Seventy-two patients were followed up for free Q max (fQ max ) PVR, IPSS and QOL score from March 2019 to June 2019 .
Results
The 72 patients were followed up for 3 to 52 months, with an average of 31.1 months. Postoperative IPSS of the three groups were(25.50±2.84), (16.78 ±4.04) and( 14.98 ±3.41), respectively. The QOL were (2.90 ±1.29), (2.67 ±0.88) and (2.53 ±0.92), respectively. The fQ max was (5.44 ±2.60), ( 10.30 ± 3.68)and(13.07 ±3.51) ml/s, respectively , and PVR was (104.00 ±46.00), (76.81 ±46.74) and (35.64 ±26.17) ml, respectively.
Interpretation of results
Compared with the preoperative parameters , QOL in group A was significantly improved , with statistically significant difference ( P < 0 . 05) and the IPSS , fQ max and PVR in group A were improved , but the difference was not statistically significant (P > 0 . 05) . The IPSS , QOL , fQ max and PVR in group B and C were significantly improved compared with the preoperative parameters ,and the difference was statistically significant (P < 0 . 05) .