Comparative analysis of organic versus conventional oils for Antimicrobial efficacy against Uropathogenic bacteria

Magdy M1, Elkasaby T2

Research Type

Clinical

Abstract Category

Prevention and Public Health

Abstract 464
Open Discussion ePosters
Scientific Open Discussion Session 102
Thursday 18th September 2025
13:50 - 13:55 (ePoster Station 6)
Exhibition
Prevention Pain, other Outcomes Research Methods Infection, Urinary Tract Conservative Treatment
1. The National Research Center in Cairo, 2. Mansoura University
Presenter
Links

Abstract

Hypothesis / aims of study
Urinary tract infections (UTIs) are considered as serious global health conundrum, the primary trigger to UTIs is pathogenic bacteria such as Escheichia Coli, Klebsiella pneumonia and staphylococcus saprophyticus. Currently, there is an overwhelming reliance on antibiotics that continuously lead to significant rise in antibiotic resistance. Thus, there must be novel alternative antimicrobial agents with clear-cut efficacy proof. This study aimed to set a comparative analysis and evaluation of Antimicrobial actions of several oils cultivated by organic and conventional farming practices against pathogenic strains of bacteria attacking Urinary Tract Systems (Uropathogenic Bacteria). 
The selected oils based on physicochemical properties were Mustard oil, Coconut oil, Sunflower oil, Sesame oil, Garlic oil and Onion Oil.
Study design, materials and methods
The methodology emplemented was the broth microdilution assay; a standardized technique for determining the minimum inhibitory concentration MIC and minimum bacterial concentration MBC of the oils against the selected bacterial strains. 
Uropathogenic bacterial suspensions were prepared with a standard concentration and some specific dilution of the oils were exposed to the strains, in order to test and record their inhibition action and neutral bactericidal effects. Controls included positive control with specific antibiotics and negative controls using solvents, were also tested to maximize the validity and reliability of the results.
Results
Results and data obtained reflected imminent Antimicrobial actions in tested oils with different variances. Moreover, distinct observations were recorded between organic and conventional oil sources, that some organic farming oils had superior inhibitory and bactericidal effects. Garlic and Coconut oils especially from organic sources indicated promising activity against E.coli and K.pneumoniae as recorded by the MIC and MBC values.
Interpretation of results
These findings highly recommend the potential of some organic farming oils as profoundly effective Antimicrobial agents to fight against Uropathogenic bacterial and UTI management.
Concluding message
Furthermore, it's recommended that further in vivo research studies and Randomized Controlled Trials (RCTs) have to be conducted in this regard for more evidence-based approaches, to move forward to more sustainable agricultural natural remedies with undeniable benefits compared to conventional counterparts of oils and antibiotics against pathogenic bacterial infections.
Disclosures
Funding The National Research Center in Cairo Clinical Trial No Subjects None
20/07/2025 21:50:27