Role of Renal Parenchyma to Hydronephrosis Area Ratio in Predicting Outcome After Pyeloplasty in Children With Ureteroplevic Junction Obstruction

El Desoukey M1, Khalil S1, Salem E1, Seleem M1, Sakr A1, Taha K1

Research Type

Clinical

Abstract Category

Paediatrics

Abstract 475
Open Discussion ePosters
Scientific Open Discussion Session 103
Thursday 18th September 2025
15:45 - 15:50 (ePoster Station 3)
Exhibition
Imaging Pediatrics Surgery Anatomy
1. Zagazig University
Presenter
Links

Abstract

Hypothesis / aims of study
The Gold standard surgical treatment for uretro-pelvic junction obstruction (UPJO) is Anderson Hynes (AH) dismembered pyeloplasty resulting in a dependent tension free anastomosis that relieves obstruction and helps functional improvement. The available ultrasound parameters that reflects functional improvement after AH are only the supportive parameters in form of decrease in the antero-posterior diameter (APD) of renal pelvis and increase in parenchymal thickness in a growing kidney.
Measurement of APD is too limited in evaluating pyeloplasty as it is a 1 dimensional measurement. So, renal parenchymal thickness to hydronephrosis area (PHAR) including renal pelvis and renal calyces in different dimensions may provide a more accurate estimate of the renal size, amount of pelvicaliectasis and possibly the renal function for prediction of pyeloplasty outcome.
Study design, materials and methods
The study included 30 children having UPJO and scheduled for open Anderson-Hynes pyeloplasty between April and October 2019. All included patients did an abdominal ultrasound to assess parenchymal thickness, PHAR, renal echogenicity. PHAR was done preoperatively and postoperatively at 3 and 6 months. Following the outline of the kidney to obtain the whole surface area of the kidney including the parenchymal (RPA) and the hydronephrosis areas. The following equations were used: RPA= total renal
area - hydronephrosis area. PHAR = Hydronephrosis area / RPA
Results
The median age of study was 9.5 years. Improvement rate after pyeloplasty was 83.3% according to clinical and radiological improvement by ultrasound and renal isotope scan. Pelvic APD and half time (T/2) postoperatively were significantly lower among improved cases, parenchymal thickness, glomerular filtration rate (GFR) and split function postoperatively was significantly higher among improved cases, and PHAR postoperatively was significantly higher among improved cases.
Interpretation of results
Pelvic APD and T ½ postoperatively showed significantly negative correlation with PHAR postoperatively while parenchymal thickness, split function, GFR total pre and postoperatively showed significantly positive correlation with PHAR postoperatively. When a cutoff value for PHAR of 1.89 is assigned to a ROC curve it showed sensitivity 84% specificity 80% for improvement.
Concluding message
PHAR can be used as a good indicator of success of pyeloplasty and improvement of renal function postoperatively with a positive correlation with renal isotope. The cutoff value of PHAR post-operatively is 1.89 with PHAR above it indicates improvement and can omitting radioisotope scans of those patients.
Disclosures
Funding Self Clinical Trial No Subjects Human Ethics Committee Institutional Review Boards (IRBs) + Egyptian Network of Research Ethics Committee Helsinki Yes Informed Consent Yes
16/07/2025 10:19:52