Hypothesis / aims of study
The Gold standard surgical treatment for uretro-pelvic junction obstruction (UPJO) is Anderson Hynes (AH) dismembered pyeloplasty resulting in a dependent tension free anastomosis that relieves obstruction and helps functional improvement. The available ultrasound parameters that reflects functional improvement after AH are only the supportive parameters in form of decrease in the antero-posterior diameter (APD) of renal pelvis and increase in parenchymal thickness in a growing kidney.
Measurement of APD is too limited in evaluating pyeloplasty as it is a 1 dimensional measurement. So, renal parenchymal thickness to hydronephrosis area (PHAR) including renal pelvis and renal calyces in different dimensions may provide a more accurate estimate of the renal size, amount of pelvicaliectasis and possibly the renal function for prediction of pyeloplasty outcome.
Study design, materials and methods
The study included 30 children having UPJO and scheduled for open Anderson-Hynes pyeloplasty between April and October 2019. All included patients did an abdominal ultrasound to assess parenchymal thickness, PHAR, renal echogenicity. PHAR was done preoperatively and postoperatively at 3 and 6 months. Following the outline of the kidney to obtain the whole surface area of the kidney including the parenchymal (RPA) and the hydronephrosis areas. The following equations were used: RPA= total renal
area - hydronephrosis area. PHAR = Hydronephrosis area / RPA
Interpretation of results
Pelvic APD and T ½ postoperatively showed significantly negative correlation with PHAR postoperatively while parenchymal thickness, split function, GFR total pre and postoperatively showed significantly positive correlation with PHAR postoperatively. When a cutoff value for PHAR of 1.89 is assigned to a ROC curve it showed sensitivity 84% specificity 80% for improvement.