Surgical treatment of Peyronie's disease is resorted to in copulatory dysfunction. Shortening (plication) correction methods have a
 number of disadvantages (first of all, the loss of the length of the penis). Despite the great complexity and risks, lengthening
 techniques are the choice of the surgeon and the patient. The main aspects determining the choice of a graft are elasticity,
 extensibility, strength, and hypoallergenic. The high risk of erectile dysfunction in corporoplasty with the use of transplants, reaches
 60%. One of the promising methods is the use of multipatent mesenchymal stem cells of the stromal vascular fraction (SVF) of
 autologous adipose tissue. The mechanism of action is due to the presence of pericytes and endotheliocytes in SVF that contribute
 to neoangiogenesis, which can reduce the risk of erectile dysfunction.

Pericardial allograft (Alloplant®) was used as a graft for corporoplasty. A preliminary assessment of the physical properties of the
 graft (strength, extensibility) were studied. The extensibility was approximately equal, both in the longitudinal and transverse
 directions. We observed the elongation of the centimeter section without loss of strength to 2 cm, the tensile strength was 2.6
 kgf/cm2. Incision and grafting with a pericardial allograft was performed on 28 patients with Peyronie's disease, without erectile
 disorders. In addition, the cavernous tissue and the tunica albuginea of corpus cavernosum of seven patients were injected with
 SVF. The transplant was covered with SVF. The average age of patients was 53±12.3 years. Patients were examined according to
 Clinical recommendations: questionnaire on the ICEF-5 scale, PDQ, pharmacodopplerography of the penis with photofixation of the
 penis in 3 prespectives, measurement of deviation using a screen protractor. The average angle of deviation of the penis was 87.5°
 (55-120°). Repeated examination was carried out 3, 6 and 12 months after the operation.

Satisfactory cosmetic results (the presence of a residual deviation of no more than 10 degrees) were achieved in 93%. The
 development of De novo erectile dysfunction of varying degrees was observed in 6 patients (28.6%) in the corporoplasty group (21
 patients). Two patients had the development of persistent erectile dysfunction with a violation of the veno-occlusive mechanism. The
 conservative methods were ineffective, therefore, the implantation of penile prosthetic is required. In the group of pericardial
 corporoplasty using SVF (7 patients), only one patient had the development of mild De novo erectile dysfunction with the effect of
 conservative therapy.

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The use of allograft pericardium (Alloplant ®) and SVF in corporoplasty is a safe, effective and affordable method of surgical
 treatment of patients with Peyronie's disease