Introduction. Prostate cancer holds a leading position among malignant tumors in men, while radical prostatectomy is one of the most effective methods for treating localized and locally advanced cancer. This paper presents the results of prostate cancer surgical treatment at our clinic, as well as our developments in surgical technique and perioperative patient care.

Objective. Analysis of our own results of surgical treatment of malignant prostate tumours using endovideosurgical technologies.

From 2021 to 2024 in the urology department of the N.I. Pirogov Clinic of High Medical Technologies SPBU performed 304 laparoscopic radical prostatectomies, including operation with pelvic lymphodissection and nerve-sparing prostatectomy. The average age of patients was 6516 years. Median of total PSA was 9.3 ng/ml (from 1.4 to 4415.8 ng/ml, including patients on androgen-deprivation therapy). Median volume of prostate was 49 cm3 (from 14 to 226 cm3). The oncological and functional results of surgical treatment are retrospectively analyzed.

The duration of surgery ranged from 100 to 505 minutes (average 209 minutes), with lymph node dissection increasing the average operation time by additional 35–85 minutes. No surgical conversions were required. Intraoperative blood loss ranged from 20 to 1000 ml (average 157 ml), and no blood transfusions were needed. Early and late postoperative complications occurred in 64 patients (21%). In the postoperative period, no severe acute somatic complications or decompensation of chronic conditions were observed. A positive surgical margin was identified in 80 patients (26%). Tumor cells were found at the resection line of the apex in 37% of cases, at the lateral surfaces in 51%, and at the base of the prostate in 12%. Among those operated on from 2021 to 2023, patient satisfaction with the quality of urination one year after surgery was 88%.

The efficiency of surgical treatment, number and nature of intra- and postoperative complications are comparable with the average of leading clinics in Russia and in the world.

The availiability of sufficient technical equipment, professional interdisciplinary team of specialists, and personalized approach to each patient allows to achieve high oncological and functional results of surgical treatment of prostate cancer.