Bladder Cancer, Histological Trends in the UAE Population: Tawam Experience as a tertiary referral center.

Bhatti A1, Salman M2, Deyab A2, Zafar M2, Afanah H2, Askhaita K3, Abduljabbar J2, Hashmath F2, Al Baloushi S2, Al Hamadi A2, Ahmad O2, M. Hidayatullah K2, Ansari J2, Husnain M2, Balaraj K4, Farghal A2, Gabriella B2

Research Type

Clinical

Abstract Category

Uro-Oncology

Abstract 501
Open Discussion ePosters
Scientific Open Discussion Session 104
Friday 19th September 2025
10:55 - 11:00 (ePoster Station 3)
Exhibition
Surgery Clinical Trial Retrospective Study
1. Skeikh Tahnoon Medical city Al Ain UAE, 2. Sheikh Tahnoon Medical City Al Ain UAE, 3. Sheikh Tahnoon Medical Al Ain UAE City, 4. Sheikh Tahnoon Medical City Al AIn
Presenter
Links

Abstract

Hypothesis / aims of study
To demonstrate the histological trends and variations amongst UAE population in the cohort of the patients presenting to Tawam hospital as a tertiary referral center.
Study design, materials and methods
Record of 139 patients were reviewed, underdoing Transurethral resection of the bladder tumour (TURBT).  This included all of transurethral resections of the bladder tumour performed during the period of January 2019 till 31st of May 22. Histology report were analysed for the tumour type, tumour grade and depth of invasion along with operation notes for tumour size and focality (unifocal/multifocal), location and the findings of the bimanual examination. These cases were subsequently reviewed at the weekly urology MDT and reviewed by the MDT uro-pathologist.
Results
Histology	                                                  Cancer grade	     Depth of Invasion	                                 Total/Percentage
Transitional cell carcinoma	                      High 	                             pT1	                                                    43           30.9%
	                                                                      High	                             pT2	                                                    36            25.8%
	                                                                      High 	                             pTa	                                                    31            22.3%
	                                                                      Low 	                             pTa	                                                    14            10.0%
	                                                                      Low 	                             pT1	                                                    1                 7.1%
Prostatic adenocarcima			                                                                                                                    5                 3.5%
Urachal 
Adeno carcimoa			                                                                                                                                     3                 2.1%
Rhadomyosarcoma 			                                                                                                                             1                 0.7%
Cervical cancer			                                                                                                                                      1                 0.7%
Poorly differentiated			                                                                                                                              1                 0.7%
Serious Carcinoma			                                                                                                                              1                 0.7%
Inflammation only 			                                                                                                                               2                1.4%
Multifocal			                                                                                                                                               133          95.6%
unifocal			                                                                                                                                                        6                4.3%
Interpretation of results
Histology	                                                  Cancer grade	     Depth of Invasion	                                 Total/Percentage
Transitional cell carcinoma	                      High 	                             pT1	                                                    43           30.9%
	                                                                      High	                             pT2	                                                    36            25.8%
	                                                                      High 	                             pTa	                                                    31            22.3%
	                                                                      Low 	                             pTa	                                                    14            10.0%
	                                                                      Low 	                             pT1	                                                    1                 7.1%
Prostatic adenocarcima			                                                                                                                    5                 3.5%
Urachal 
Adeno carcimoa			                                                                                                                                     3                 2.1%
Rhadomyosarcoma 			                                                                                                                             1                 0.7%
Cervical cancer			                                                                                                                                      1                 0.7%
Poorly differentiated			                                                                                                                              1                 0.7%
Serious Carcinoma			                                                                                                                              1                 0.7%
Inflammation only 			                                                                                                                               2                1.4%
Multifocal			                                                                                                                                               133          95.6%
unifocal			                                                                                                                                                        6                4.3%
Concluding message
Patient referred to or presenting to Tawam Hospital, Contrary to the peer review reports where low grade non muscle invasive carcinoma is the most common variant. This Cohort had high grade pT1 as most common histological variant, followed by high grade Muscle invasive pT2 , high grade pTa is the next most common histological subtype.  Low grade pTa /T1 the least common sub type.
Tawam experience of bladder cancer histology demonstrating different histological trends and variations.  Broader studies are needed to assess histological variations within the UAE papulation.
Disclosures
Funding none Clinical Trial No Subjects Human Ethics not Req'd this is an audit of the results Helsinki not Req'd Audit Informed Consent Yes
16/07/2025 16:32:57