Autologous vs synthetic bandlets in sacrocolpopexy : a single center study

Chommeloux M1, BLONDEAU A2, HAUDEBERT C1, RICHARD C1, FAURIE B1, DUBOIS A1, PENAFIEL J1, MANUNTA A1, HASCOET J1, PEYRONNET B1

Research Type

Clinical

Abstract Category

Pelvic Organ Prolapse

Abstract 55
Urogynaecology 2 - Pelvic Organ Prolapse
Scientific Podium Short Oral Session 5
Thursday 18th September 2025
11:45 - 11:52
Parallel Hall 3
Pelvic Organ Prolapse Grafts: Biological Grafts: Synthetic
1. CHU Rennes, 2. CHU Nancy
Presenter
Links

Abstract

Hypothesis / aims of study
Robotic sacrocolpopexy is one of the most common surgical treatment for POP, and is mostly performed using synthetic bandlets made of polypropylene. However, due to the recent controversy on synthetic materials, a new technique using autologous membrane bandlets has developed. The aim of the present study was to compare the  outcomes of autologous vs synthetic bandlets in sacrocolpopexy.
Study design, materials and methods
The charts of all consecutive patients who underwent robotic sacrocolpopexy for POP at a single academic center between 2013 and 2023 were retrospectively reviewed. Procedures including rectopexy were excluded. The autologous membrane bandlets technique was developed in 2022. From this moment, it was mostly used for patients with history of explanted sacrocolpopexy bandlets for complications (pain, bladder extrusion, vaginal exposition) or patients refusing synthetic materials.
Results
65 patients were included in the present analysis : 11 in the autologous group and 54 in the synthetic group. The autologous membrane was fascia late in 10 cases and rectus abdominus muscle in 1 case.
Interpretation of results
The mean operative time was not significantly different between the two groups (190 vs 165 min ; p = 0,14). The mean length of hospital stay was significantly longer in the autologous group (4,2 vs 1,8 days ; p = 0,007). The readmission rate was not different between the two groups (18 vs 2% ; p = 0,08) ; moreover, the rate of new surgery for POP relapse was not different between the two groups, but was higher in the synthetic group (0 vs 3,8% ; p = 0,99). At 3 month follow-up, there was no difference between the two groups in term of rate of Baden-Walker grade ≥ 1 cystocele or uterine prolapse (10 vs 7,9% ; P = 0,98) or in term of rate of PGII 1 or 2 (100 vs 91% ; p = 0,99). At last follow-up, those two outcomes were not significantly different either (prolapse : 0 vs 6% ; p = 0,99 - PGII : 100 vs 95% ; p = 0,27). However, the PGII 1 or 2 rate for autologous bandlets was always 100%. The mean follow-up time was similar (6 vs 17 month ; p = 0,64).
Concluding message
Autologous bandlets seem like a fine alternative option to synthetic bandlets for specific cases. However, there was more morbidity with autologous bandlets, as seen with the extended length of hospital stay.
Figure 1 Results
Disclosures
Funding None Clinical Trial No Subjects Human Ethics not Req'd is was a retrospective study using the patients files Helsinki Yes Informed Consent No
10/07/2025 21:23:22