Efficacy of right hypogastric nerve excision (Alaa Aglan(6) operation) for premature ejaculation treatment

Aglan A1

Research Type

Clinical

Abstract Category

Andrology

Abstract 602
Open Discussion ePosters
Scientific Open Discussion Session 106
Friday 19th September 2025
15:50 - 15:55 (ePoster Station 1)
Exhibition
Surgery Sexual Dysfunction Male
1. Alaa Clinic Hospital
Presenter
Links

Abstract

Hypothesis / aims of study
presentation of new operation – Alaa Aglan (6) - for treatment of cases not responding to local anesthetics. We excise the right hypogastric nerve at the distance between hypogastric trunk bifurcation and pelvic ganglia (usually after bifurcation directly) Fig1.
Study design, materials and methods
20 patients underwent surgery (2016/2/27 – 2016 /8/23) at Alaa Clinic hospital, Egypt.
Criteria: Age (21 – 47), hetro sexual, No response to local anesthetics or good response to alcohol, ejaculation time less than 30 seconds.
Approach: modified Maylard incision 
We cut the right hypogastric nerve directly after bifurcation of hypogastric trunk then we dissect the distal end and pull it towards pelvis to prevent reunion and allow re-suturing if needed (we didn’t cut a segment from the nerve).
Results
After six months follow up period, one patient reported improvement of ejaculation time till 15 minutes, two patients reported 8 minutes, fifteen patients reported (3 – 4) minutes, one patient reported one minute ( previously ejaculation was immediately before entrance ), two patients reported wound seroma ( early removal of the drain ), one patient reported internal bleeding. Exploration was done we found bleeding from rectus muscles. We suture the muscle carefully and no blood transfusion was needed, most of patients reported wet dreams in first week, retrograde ejaculation was not reported.
Interpretation of results
the hypogastric nerve fibers shows crossing at bifurcation level and pelvic ganglia level, so cutting of the nerve at right side could be compensated. If we cut the nerves, bilaterally retrograde ejaculation occurs . Wet dreams are most likely due to nerve manipulation. Theoretically, we can do a test before excision of the right hypogastric nerve. We can inject local anesthesia at right hypogastric nerve after bifurcation area directly and stimulate the left branch electrically, if ejaculation occurs this means it is safe to excise the nerve and vice versa ( but actually we didn’t apply this test in this study ). Also theoretically, we can use electrical devices like vagal inhibition unilaterally or bilaterally or even at the trunk itself but the cost is too much so we did not try to use it in this study.
Concluding message
Alaa Aglan(6) operation is a promising treatment for premature ejaculation; more studies are needed to clarify its safety and efficacy.
Figure 1
Disclosures
Funding None Clinical Trial Yes Public Registry No RCT No Subjects Human Ethics not Req'd This study did not require ethics committee approval cause it is safe and no side effects and The patients are aware of all the details and agrees to them. Helsinki Yes Informed Consent Yes
16/07/2025 05:52:12