Validation of the Persian Version of the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and Nocturia Quality of Life (ICIQ-Nqol)

Jahantabi E1, Alamdari G2, Tayebi S3, Attar A4, Hemmati M2, Tapak M5, Salehi-Pourmehr H6, Hajebrahimi S7

Research Type

Clinical

Abstract Category

Nocturia

Abstract 624
Open Discussion ePosters
Scientific Open Discussion Session 107
Saturday 20th September 2025
10:40 - 10:45 (ePoster Station 1)
Exhibition
Nocturia Questionnaire Female
1. Department of Urology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran, 2. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran., 3. Urology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., 4. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran., 5. Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran, 6. Research Center for Evidence-based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran, 7. Department of Urology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Presenter
Links

Abstract

Hypothesis / aims of study
Nocturia, particularly when occurring two or more times nightly, significantly diminishes quality of life. Validated patient-reported outcome measures like the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and Nocturia Quality of Life (ICIQ-Nqol) are essential for assessing its impact. This study aimed to translate the ICIQ-N and ICIQ-Nqol into Persian and rigorously evaluate the validity and reliability of these translated versions for use in Persian-speaking populations.
Study design, materials and methods
This methodological study involved the translation and validation of the ICIQ-N and ICIQ-Nqol. The standard forward-backward translation process was employed, with review by the ICIQ group and urologists. Content validity was assessed through qualitative feedback and quantitative measures (CVI and CVR) from ten experts. Internal consistency was evaluated using Cronbach's alpha. Construct validity was examined via exploratory factor analysis (EFA) with principal components analysis (PCA) on data from 208 Iranian women with lower urinary tract symptoms. Sampling adequacy (KMO) and factorability (Bartlett’s test) were assessed. Test-retest reliability was determined over a 14-day interval in the same participants by calculating the intraclass correlation coefficient (ICC). Statistical analysis was performed using SPSS version 26 (p < 0.05).
Results
The Persian ICIQ-N and ICIQ-Nqol were completed by 208 female patients. Content validity assessment yielded acceptable CVI and CVR values for all items. Cronbach’s alpha demonstrated good internal consistency for ICIQ-N (0.888) and excellent internal consistency for ICIQ-Nqol (0.974). EFA supported the construct validity, with a factor structure aligning with the theoretical concepts and adequate KMO and significant Bartlett’s test results. Test-retest reliability showed good to excellent ICC values for both questionnaires (p < 0.05). Descriptive analysis of ICIQ-Nqol responses highlighted that while a subset reported minimal bother, a significant proportion experienced severe impact on concentration, energy, productivity, and daily life, often leading to fluid restriction and worry about condition worsening.
Interpretation of results
The Persian translations of the ICIQ-N and ICIQ-Nqol demonstrate robust psychometric properties, including good content validity, strong internal consistency, and reliable test-retest scores in Iranian women with lower urinary tract symptoms. The factor structure supports the underlying constructs of nocturia frequency and its impact on quality of life. These findings indicate that the Persian versions are valid and reliable tools for assessing nocturia in Persian-speaking populations, enabling standardized data collection in clinical practice and research.
Concluding message
The validated Persian versions of the ICIQ-N and ICIQ-Nqol provide essential tools for accurately assessing nocturia and its impact on quality of life in Persian-speaking individuals. Their availability will facilitate standardized data collection, improve clinical management, and enable meaningful cross-cultural research in the field of nocturia.
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee Tabriz University of Medical Sciences Helsinki Yes Informed Consent Yes
04/07/2025 13:44:20