Study design, materials and methods
This retrospective cohort study included 166 women who underwent posterior colporrhaphy between 2014 and 2023 at Soroka University Medical Center. Analysis was performed on 138 women for whom diabetes status and relevant clinical data were available. Demographic, clinical, and surgical characteristics were compared between diabetic and non-diabetic patients. Postoperative complications were assessed over a 12-month follow-up period and classified according to the Clavien-Dindo system. Univariate and multivariate logistic regression analyses were performed to identify independent associations between diabetes and complications, adjusting for potential confounders including age, hypertension, and menopausal status.
Results
Among women with complete data, 65.7% of diabetic patients experienced at least one postoperative complication compared to 58.3% of non-diabetic patients; this difference was not statistically significant. Diabetic patients were significantly older (62.7 vs. 55.6 years, p=0.002), had higher rates of hypertension (40% vs. 14.6%, p=0.001), and were less frequently postmenopausal (32.6% vs. 67.4%, p=0.035). Mean HbA1c levels were 7.15% in diabetic patients and 5.6% in non-diabetics. In multivariate analysis controlling for age, hypertension, and menopausal status, diabetes was not independently associated with postoperative complications.
Interpretation of results
Although diabetic patients had higher rates of age-related and metabolic comorbidities, diabetes itself was not independently associated with postoperative complications. This suggests that the presence of diabetes may reflect underlying risk factors rather than serving as a direct predictor of surgical outcomes. When adjusted for key confounders, diabetes did not appear to contribute additional risk, indicating that posterior colporrhaphy can be considered safe in well-selected diabetic patients under appropriate clinical management.