Early and Aggressive Debridement Decreases Mortality in Fourniers Gangrene-Retrospective

Alblooshi S1, Khan M1

Research Type

Clinical

Abstract Category

Quality of Life / Patient and Caregiver Experiences

Abstract 767
Open Discussion ePosters
Scientific Open Discussion Session 109
Saturday 20th September 2025
15:50 - 15:55 (ePoster Station 6)
Exhibition
Infection, other Male Pain, Pelvic/Perineal Surgery
1. STMC
Presenter
Links

Abstract

Hypothesis / aims of study
Fournier’s gangrene G) is a rare necrotizing fasciitis affecting genital and perianal
 areas. This study aimed to review the micro biology of blood cultures and the mortality
 associated in patients with this rare condition at a tertiary referral center.
Study design, materials and methods
This study included a retrospective analysis of patients diagnosed
Results
A total of 28 patients were included in the study. The average age of the patients was
56.2 years. Among these patients, 4 out of 28 (14.2%) died, reflecting a lower-than-expected
mortality rate compared to previously reported ranges in the literature. Positive blood cultures were observed in 4 patients (14.2%), while urine cultures were positive in 3 patients (10.7%).
The average time from initial assessment to surgical intervention (time to OR) was 4.5 hours,
highlighting the emphasis on rapid debridement in managing this condition.
Interpretation of results
The study included a total of 28 patients, with an average age of 56.2 years, indicating a middle-aged population affected by the condition under investigation. The mortality rate observed in this cohort was 14.2% (4 out of 28 patients), which is notably lower than what has been reported in previous studies. This may suggest improvements in early recognition, aggressive management, or surgical intervention strategies.

Positive blood cultures were identified in 14.2% of patients, while urine cultures were positive in 10.7%. These relatively low rates of positive cultures might reflect early antibiotic administration or the variable microbial profile associated with the condition.

Importantly, the average time to surgical intervention was 4.5 hours, emphasizing the priority placed on rapid debridement. This swift approach to operative management may have contributed significantly to the lower mortality rate, underlining the importance of timely surgical response in improving outcomes for these patients.
Concluding message
Although the quoted mortality rates are between 20 and 40% in most cases, and range from
4 to 88%. We have found very low mortality in our case series , it this is probably secondary to early aggressive debridement and broad-spectrum antibiotic coverage which help reduce
this mortality.
Also of note blood cultures are negative in a majority of the patients and it is imperative that patients are started on appropriate triple therapy to reduce the morbidity and mortality.
Disclosures
Funding No funding Clinical Trial No Subjects Human Ethics Committee Seha Helsinki Yes Informed Consent Yes
16/07/2025 01:07:19