Revolutionizing Treatment: Emerging Therapies for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

Padmanaban H1, Mohsin M1, Shingal A1

Research Type

Clinical

Abstract Category

Pelvic Pain Syndromes

Abstract 844
Non Discussion Abstracts
Scientific Non Discussion Abstract Session 400
Painful Bladder Syndrome/Interstitial Cystitis (IC) Quality of Life (QoL) Neuromodulation
1. Birmingham Heartlands Hospital, University Hospitals Birmingham NHSFT
Links

Abstract

Hypothesis / aims of study
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a complex, often debilitating condition that causes chronic pelvic pain and urinary symptoms, significantly impacting quality of life. Despite its prevalence, many patients find limited relief from traditional treatments. Fortunately, groundbreaking therapies are emerging that promise to transform the management of IC/BPS. This presentation explores the most exciting new treatment options, from novel intravesical therapies to cutting-edge neuromodulation techniques and regenerative medicine.

Objective:
To explore the latest innovations in IC/BPS treatment, highlighting therapies that offer fresh hope for patients, and discussing their potential to reshape the future of care.
Study design, materials and methods
This review examines recent clinical trials and research on promising treatments, including liposomal formulations, botulinum toxin, neuromodulation, and stem cell therapy, offering a glimpse into the next generation of IC/BPS care.
Results
1.	Intravesical Therapies: Liposome-based drug delivery systems are enhancing the effectiveness of treatment by targeting the bladder lining more precisely, improving symptom control.
	2.	Botulinum Toxin: For patients with severe, refractory symptoms, botulinum toxin injections are providing much-needed relief, reducing bladder pain and urgency when other treatments fail.
	3.	Neuromodulation: Both sacral nerve stimulation and percutaneous tibial nerve stimulation are emerging as non-invasive, highly effective therapies, helping patients regain control over their bladder function and reduce pain.
	4.	Regenerative Medicine: Stem cell therapy holds exciting potential for healing damaged bladder tissue, addressing inflammation, and offering longer-term solutions to IC/BPS symptoms.
Interpretation of results
These emerging therapies mark a new chapter in the treatment of IC/BPS, providing patients with more effective and personalized options. However, while early results are promising, further research and larger trials are needed to confirm long-term benefits and refine treatment protocols.
Concluding message
The future of IC/BPS management is rapidly evolving with innovative therapies that promise to improve patient outcomes and quality of life. With continued research and the advent of personalized treatments, there is real hope for transforming care and offering lasting relief for IC/BPS sufferers.
Disclosures
Funding No sources to disclose Clinical Trial No Subjects None
06/07/2025 12:39:57