ICS 2011 Scientific Podium Poster Session S17 - Urothelium and Signal Transmission

	Thursday 1st September 2011
	16:00 - 17:30
	Hall P4

16:30

#177 A next generation drug for Overactive bladder, TRK-130, in a Phase-IIb clinical trial in Japan; Preclinical data of potent pharmacological effects based on modulation of neurotransmission.

Presenter: Koji Kawai

Kawai K¹, Fujimura M¹, Kanie S¹, Momen S¹, Izumimoto N¹, Iwata M², Okanishi S², Hashimoto T², Awasaki Y², Nishida N², Sasaki M³, Yanagita T⁴
1. Toray Industries Inc. Pharmaceutical Research Laboratories, 2. Takeda Pharmaceutical Company Limited, 3. Ina research Inc., 4. Jikei University School of Medicine

16:35

#178 HIGH-DOSE TRANILAST CREATES INTERSTITIAL CYSTITIS WITH INCREASED VESICAL VASCULAR PERMEABILITY IN RATS

Presenter: Saori Nishijima

Nishijima S¹, Sugaya K¹, Kadekawa K¹, Ashitomi K¹, Yamamoto H²
1. Southern Knights' Laboratory LLP, 2. Department of Biochemistry, University of the Ryukyus

16:40

#179 Enhanced bladder pain in cyclophosphamide-induced cystitis in rats- Involvement of pelvic nerve and hypogastric nerve sensitization

Presenter: Tomohiko Oguchi

Oguchi T¹, Yokoyama H¹, Yoshikawa S¹, Nishizawa O², Yoshimura N¹
1. University of Pittsburgh, 2. Urology, Shinshu University

16:45

#180 Impact of Diabetes Mellitus on Bladder Uroepithelial Cells.

Presenter: Ann Hanna-Mitchell

Hanna-Mitchell A¹, Wolf-Johnston A¹, Ruiz W¹, Apodaca G¹, Daneshgari F², Birder L¹
1. University of Pittsburgh, 2. Case Western Reserve University

16:50

#181 EFFECTS OF a1-BLOCKER ON THE RELEASE OF ATP AND PROSTAGLANDIN E2 FROM THE URETHRAL EPITHELIUM IN BOO RATS

Presenter: Keiko Nagase

Nagase K¹, Tanaka I¹, Zha X¹, Kusukawa N¹, Ito H¹, Aoki Y¹, Oyama N¹, Miwa Y¹, Akino H¹, Yokoyama O¹
1. The Department of Urology, Faculty of Medical Science, University of Fukui

16:55

#182 EVALUATIONS OF INCREASED VOIDING FREQUENCY IN MICE WITH DIABETES MELLITUS AT EARLY STAGE

Presenter: Mitsuharu Yoshiyama

Yoshiyama M¹, Mochizuki T², Nakagomi H³, Miyamoto T³, Kobayashi H³, Zakoji H³, Takeda M³
1. Yumura Onsen Hospital, 2. Yamanashi-Kosei Hospital, 3. Department of Urology, University of Yamanashi Interdisciplinary Graduate School of Medicine and Engineering

17:00

#183 SPINAL GLYCINE TRANSPORTER-1 INHIBITION INFLUENCES THE MICTURITION REFLEX IN URETHANE-ANESTHETIZED RATS

Presenter: Seiya Inoue

Honda M¹, Kawamoto B¹, Panagiota T¹, Iwamoto H¹, Inoue S¹, Matsumoto M¹, Morizane S¹, Yao A¹, Hinata N¹, Isoyama T¹, Sejima T¹, Takenaka A¹
1. Department of Urology, Faculty of Medicine, Tottori University

17:05

#184 Pharmacokinetics of imidafenacin, a novel antimuscarinic agent, may contribute largely to the bladder-selective pharmacological effects

Presenter: Shizuo Yamada

Ito Y¹, Ogoda M¹, Niiya R¹, Yamada S¹
1. University of Shizuoka

17:10

#185 ENDOTHELIN ETB RECEPTORS ARE INVOLVED IN THE RELAXATION OF THE PIG URINARY BLADDER NECK: A POSSIBLE THERAPEUTICAL TARGET FOR URINARY INCONTINENCE PRODUCED BY INTRINSIC SPHINCTERIC DEFICIENCY.

Presenter: Salvador Bustamante

Bustamante S¹, Arteaga J L², Orensanz L M³, Martínez M P⁴, Martínez-Sáenz A², Fernandes V S², Ribeiro A S F², Carballido J¹, García-Sacristán A², Prieto D², Hernández M²
1. Servicio de Urología, Hospital Puerta de Hierro de Majadahonda, Madrid, 2. Departamento de Fisiología, Facultad de Farmacia, Universidad Complutense de Madrid, 3. Departamento de Investigación, Hospital Universitario Ramón y Cajal de Madrid, 4. Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad Complutense de Madrid

17:15

#186 The role of the urothelium in potassium sensitivity testing in the clinic.

Presenter: Laura J Gooch

Gooch L J¹, Daly D M¹, Chapple C R², Grundy D¹
1. The University of Sheffield, 2. Royal Hallamshire Hospital

17:20

#187 Expression of the the Degenerin/Epithelial Na+ Channel (Deg/ENaC) and the Acid-Sensing Ion Channel (ASIC) Family in the urothelium of patients with spinal cord injury and neurogenic detrusor overactivity

Presenter: Giulio Del Popolo

Del Popolo G¹, Mencarini M¹, Neli F¹, Vannucchi M G², Pelegrini Faussone M T², Lazzeri M¹
1. Osp. Careggi -FI, 2. University Florence

17:25

#188 Urothelial release of nerve growth factor (NGF): modulation by protein kinase C and mitogen-activated protein kinase pathways

Presenter: Peter Ochodnicky

Ochodnicky P¹, Michel M B¹, Seth J H², Game X², Panicker J², Fowler C J², Michel M C¹
1. Dept. Pharmacology and Pharmacotherapeutics, Amsterdam Medical Center, University of Amsterdam, the Netherlands, 2. Dept. of Uro-Neurology, National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, London, United Kingdom

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Urothelium and Signal Transmission

Scientific Podium Poster Session S17

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