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Research Type
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Pure and Applied Science / Translational |
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Keywords
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Ageing bladder homeostasis |
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Target Audience
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Clinicians and scientists interested in the basic science and clinical translation of adaptive urinary control physiology and the impact of ageing. |
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Aims and Objectives
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Urinary disorders are common and morbid in the aged, yet are too often poorly addressed by a bladder pressure/volume-centric paradigm. A systemic approach is needed. This workshop will reconsider urinary control physiology as integrative control providing biologic adaptability to bladder filling and voiding, gained by maturation and progressively compromised in the ageing system. Loss of resilience with ageing increases the likelihood of urinary disorders but does not preclude adaptive performance. We will specifically focus on the basic science and clinical impact of the bladder as an adjustable sensor and actuator in an ageing homeostatic system. Research and clinical impacts will be discussed among the panel and participants.
Learning Objectives - 1. Attendees will understand the concept of homeostasis and its application to urinary function.
2. Attendees will be able to describe an adaptive model of neuroendocrine control of bladder response to volume.
3. Attendees will be able to state ways in which ageing can compromise adaptive capabilities, increasing the risks of homeostatic failure.
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