A 3-day voiding diary is a useful tool in evaluation of severe primary nocturnal enuresis in children

Zhang H1, Yang J1, Wu G2, Si G3, Wen Y1, Jia W4, Hu J4, Wen J1

Research Type

Clinical

Abstract Category

Paediatrics

Abstract 358
Open Discussion ePosters
Scientific Open Discussion Session 101
Thursday 18th September 2025
10:35 - 10:40 (ePoster Station 3)
Exhibition
Nocturnal Enuresis Pediatrics Voiding Diary Voiding Dysfunction
1. Henan Joint International Pediatric Urodynamic Laboratory, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China, 2. Department of Urology, Children Hospital of Dongguan City, Dongguan 523888, China, 3. Department of Urology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China, 4. Department of Urology, Women and Children Hospital of Guangzhou, Guangzhou 510030, China
Presenter
Links

Abstract

Hypothesis / aims of study
This is an original study that aims to investigate the feasibility and clinical significance of a 3-day voiding diary (VD) for assessing severe primary nocturnal enuresis (PNE) in children.
Study design, materials and methods
A multicenter prospective study was conducted on 141 children (aged 6–14 years) diagnosed with severe enuresis (≥4 nights/week) according to the International Children’s Continence Society (ICCS) criteria [1], from January to December 2023. Participants were divided into non-monosymptomatic enuresis (NMNE) and monosymptomatic enuresis (MNE) groups based on the presence or absence of daytime lower urinary tract symptoms [1]. Each child completed a 2-week VD, from which 3-day VD data (Friday, Saturday, and Sunday) were extracted. VD parameters between the 2-week and 3-day VD were compared.
Results
A total of 128 children completed the 2-week VD (87 MNE, 41 NMNE). Among the 87 MNE patients, 51 were male and 36 were female, with a mean age of 9.20±2.193 years (range: 6-14 years) and a BMI of 16.91±2.384. The 41 NMNE patients included 21 males and 20 females, with a mean age of 9.95±2.674 years (range: 6-15 years) and a BMl of 16.97±1.879. No statistically significant differences were observed between the 2-week and 3-day VD in the following parameters: average daily voiding frequency, average voided volume/expected bladder capacity (EBC), average maximum voided volume, average maximum voided volume/EBC, average total nocturnal voided volume, and average total nocturnal voided volume/EBC (all P > 0.05). Positive correlations were found between the 3-day and 2-week VD data for average voided volume (AVV) in both MNE (r = 0.876, P < 0.05) and NMNE groups (r = 0.801, P < 0.05). The treatment plans based on VD results achieved satisfactory outcomes.
Interpretation of results
Nearly 10% of the patients included in this study did not complete the 2-week VD, indicating that the compliance of the 2-week VD still needs to be improved. The results showed that there was no statistical difference in the parameters of 3-day and 2-week VD in children with severe MNE and NMNE (P > 0.05). In the MNE and NMNE patient groups, the AVV recorded for 3-day and 2-week VD was positively correlated and had a strong correlation (P < 0.05). It is indicated that 3-day VD can completely replace 2-week VD to evaluate the condition of children with severe PNE.
Concluding message
A 3-day VD might replace the 2-week VD for evaluating both severe MNE and NMNE in children and guide personalized clinical management.
Figure 1 Table1. Comparison of 2-week and 3-day VD parameters in children with MNE (n=87)
Figure 2 Table2. Comparison of 2-week and 3-day VD parameters in children with NMNE (n=41)
References
  1. Austin PF, Bauer SB, Bower W, et al. The standardization of terminology of lower urinary tract function in children and adolescents: update report from the Standardization Committee of the International Children's Continence Society [J]. J Urol, 2014, 191(6): 1863-1865.e1813. DOI: 10.1016/j.juro.2014.01.110.
Disclosures
Funding This study was supported by the National Natural Science Foundation of China (82470807) Clinical Trial No Subjects Human Ethics Committee Ethics Committee of the First Affiliated Hospital of Zhengzhou University (2022-KY-0691) Helsinki Yes Informed Consent Yes
07/07/2025 13:11:33