International Continence Society

Principal Investigator/Program Director (Last, First, Middle): DuBeau, Catherine E.________________________

BIOGRAPHICAL SKETCH
Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.

NAME
DuBeau, Catherine Esther POSITION TITLE
Professor of Medicine
University of Massachusetts Medical School

eRA COMMONS USER NAME

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION DEGREE
(if applicable) YEAR(s) FIELD OF STUDY
Bryn Mawr College, Bryn Mawr, PA AB 1980 English Literature
University of Connecticut School of Medicine MD 1985 Medicine

1. Positions and Honors
   1985 88 Resident in Primary Care Internal Medicine, Beth Israel Hospital, Boston, MA
   1988 92 Fellow in Geriatrics, Division on Aging, Harvard Medical School
   1988 Kellogg Fellowship, Harvard School of Public Health, Boston, MA
   1988-03 Staff/Research physician, Hebrew Rehabilitation Center for Aged, Boston
   1989-91 Urodynamic Fellowship, West Roxbury VAMC/Harvard Medical School
   1992-94 Associate Physician, Brigham and Women's Hospital, Boston, MA
   1994-97 Instructor in Medicine, Harvard Medical School, Boston, MA
   1994-03 Associate Physician, Beth Israel Deaconess Medical Center, Boston, MA
   1994-03 Physician, Urban Medical Group, Boston, MA
   1997-99 Assistant Clinical Professor of Medicine, Harvard Medical School, Boston, MA
   1999-03 Assistant Professor of Medicine, Harvard Medical School, Boston, MA
   2001-03 Executive Committee, Joint Center on Aging, Beth Israel Deaconess Med Center, Boston, MA
   2001-03 Operations Committee, Education Chair, and Attending Physician, Acute Care of Vulnerable Elderly (ACOVE) Inpatient Geriatric Unit, Beth Israel Deaconess Medical Center, Boston, MA
   2002-03 Director, Academic Geriatrics, Gerontology Division, Beth Israel Deaconess Med Ctr, Boston
   2003-08 Associate Professor of Medicine, Section of Geriatrics, University of Chicago
   2003-present Attending Physician, University of Chicago Hospitals and Outpatient Senior Health Center at South Shore, Chicago, IL
   2003-present Director, Geriatric Continence Center, University of Chicago Hospitals, Chicago, IL
   2004 American Geriatric Society – National Association for Continence: Continence Champion Award
   2006 The Lancet Travel Grant
   2008 University of Chicago Department of Medicine Excellence in Medical Education and Clinical Care Award
   2008 American Geriatric Society Special Recognition Award for Outstanding Service to the Quality Performance and Measurement Committee
   2008-2009 Professor of Medicine, Section of Geriatrics, University of Chicago
   2009-present Clinical Chief of Geriatrics, UMassMemorial Health Center, Worcester, MA
   2009-present Professor of Medicine, Departments of Medicine, Family Medicine and Community Health, and Obstetrics and Gynecology, University of Massachusetts School of Medicine, Worcester, MA

Other Experience and Professional Memberships
1993-present American Federation for Aging Research, National Scientific Review Committee.
1993-96 Task Force on Prostate Cancer Screening, Mass. Chapter, American Cancer Society.
1994-03 Member, Board of Directors, Urban Medical Group, Jamaica Plain, MA.
1994-00 Advisory Committee, MA Dept. of Public Health, Prostate Cancer Awareness Project
1997-present Editorial Board, Journal of the American Geriatrics Society
1998 Consultant reviewer, Department of Veterans Affairs, Office of External Reviews
2000-01 American Geriatric Society Ad Hoc Task Force on Bladder Control Problems in Older Adults, initial development of HEDIS measure for urinary incontinence
2000 Member, Geriatrics Committee, WHO International Consultation on Incontinence
2000-03 Member, Quality Improvement Committee, Beth Israel Deaconess Medical Center, Boston, MA
2001-02 Urinary Incontinence Technical Subgroup, National Committee for Quality Assurance, developing HEDIS measure for urinary incontinence
2001-03 Executive Committee, Division on Aging, Harvard Medical School
2003-present Co-Chair, Geriatrics Committee, WHO, International Consultation on Incontinence
2005 Scientific Review Committee, Population Research/Reproductive Sciences SubCommittee, Council CHHD-G RS
2005 Ad hoc reviewer, Ontario [Canada] Ministry of Health and Long-Term Care, Health Research Personnel Award
2006-present Standardization Committee, International Continence Society
2005-06 Expert reviewer, ACOVE-3 (Assessing Care of the Vulnerable Elderly) Potential Quality Indicators and Literature Review: Urinary Incontinence, Rand Corporation; this is the second update of the ACOVE project to develop Quality Measures tools for frailer older persons.
2005-09 Board of Directors, National Association for Continence
2006-09 Geriatrics Work Group Member, American Geriatrics Society/AMA Physicians Consortium for Performance Improvement, Development of Falls, Urinary Incontinence, End of Life Care and Care Coordination Performance Measures
2006-07 Planning Committee, NIH State-of-the Science Conference on Fecal and Urinary Incontinence
2007- Chair, Frail Elderly Committee, WHO, International Consultation on Incontinence
2007 NIH Scientific Review Committee, NIH Center for Scientific Review Special Emphasis Panel, Council ZRG1 HOP-U (40): SCORS
2007- Quality Measurement and Performance Committee, American Geriatric Society
2007 Reviewer, Health Resources and Services Administration, US Dept of Health and Human Services, Geriatric Academic Career Award program (HRSA-07-GACA)
2007 Editorial Board, Neurourology and Urodynamics
2007-09 Member, Department of Medicine Quality Improvement Committee, University of Chicago
2008- Agency for Healthcare Research and Quality Technical Expert Panel, Etiology and Treatment Alternatives for Overactive Bladder in Women, Vanderbilt University Evidence-based Practice Center
2008- Clinical advisor, Geriatrics program, Foundation for Informed Medical Decision Making
2008 Associate Editor, Journal of the American Geriatrics Society

2. Selected publications (from over 70 papers and chapters)

1. DuBeau CE, Voytovich AE, Rippey RM. Premature conclusions in the diagnosis of iron deficiency anemia:
   Cause and effect. Med Decis Making 1986;6(3):169 173.

2. DuBeau CE, Resnick NM. Evaluation of the causes and severity of geriatric incontinence: A critical
   appraisal. Urol Clin N Amer 1991;18(2):243 256.

3. DuBeau CE, Resnick NM. Controversies in the evaluation and treatment of benign prostatic hypertrophy.
   Advances Int Med 1992;37:55-83

4. Branch LG, Walker LA, Wetle TT, DuBeau CE, Resnick NM. Urinary incontinence knowledge among
   community-dwelling people 65 years of age and older. J Amer Geriatr Soc 1994;42:1257-61.

5. DuBeau CE, Sullivan MP, Cravalho E, Resnick NM, Yalla SV. Correlation between micturitional urethral
   pressure profile and pressure-flow criteria in bladder outlet obstruction. J Urol 1995;154:498-503.

6. DuBeau CE, Yalla SV, Resnick NM. Implications of the Most Bothersome prostatism symptom for clinical
   care and outcomes research. J Amer Geriatr Soc 1995;43: 985-92.

7. Branch L, Resnick N, DuBeau CE, et al. Knowledge, attitudes, and practices of physicians regarding
   urinary incontinence in persons aged > 65 years—Massachusetts and Oklahoma, 1993. MMWR
   1995;44(40):747,753-4.

8. DuBeau CE, Resnick NM. Urinary incontinence and dementia: the perils of guilt by association. [Editorial].
   J Amer Geriatr Assoc 1995;43:310-11.

9. DuBeau CE, Resnick NM. Editorial comment re: Wagner TH, Patrick DL, Bavendam TG, Martin ML,
   Buesching DP. Quality of life of people with urinary incontinence: development of a new measure. Urology
   996; 47:67-72.

10. DuBeau CE. Interpreting the effect of common medical conditions on voiding dysfunction in the elderly.
    Urol Clin N Amer 1996;23:11-18.

11. DuBeau CE. Problems in voiding and diseases of the prostate. In: Wei JY, Sheehan MN, eds. Geriatric
    Medicine: a case-based manual. New York: Oxford University Press, 1997:pp149-159.

12. DuBeau CE, Levy B, Mangione CM, Resnick N. Impact of urge urinary incontinence on quality of life:
    importance of patients’ perspective and explanatory style. J Amer Geriatr Soc 1998;46:683-92. Related
    editorial: Wyman JF. J Amer Geriatr Soc 1998;46:778-779.

13. DuBeau CE, Yalla SV, Resnick NM. Improving the utility of urine flow rate to exclude outlet obstruction in
    men with voiding symptoms. J Amer Geriatr Soc 1998;46:1118-1124.

14. DuBeau CE, Kiely DK, Resnick NM. Quality of life impact of urge incontinence in older persons: a new
    measure and conceptual structure. J Amer Geriatr Soc 1999;47:989-994.

15. DuBeau CE. Clinical presentation and diagnosis of urinary incontinence; Epidemiology, risk factors, and
    pathogenesis of urinary incontinence; and Treatment of urinary incontinence. In: UpToDate, Rose BD (Ed),
    UpToDate, Inc., Wellesley, MA 1999-present.

16. DuBeau CE. Urinary Incontinence. In: Geriatric Review Syllabus, 4th, 5th, and 6th ed., American Geriatrics
    Society, 1999-2005.

17. DuBeau CE. Urinary Incontinence. In: Evans JG, Williams TF, Beattie BL, Michel J-P, Wilcock GK, eds.
    Oxford Textbook of Geriatric Medicine, 2nd ed. Oxford University Press, 2000, pp677-89.

18. DuBeau CE. Urinary Incontinence Management: New Questions from Old Assumptions [Editorial] J Amer
    Geriatr Soc 2001;49(6):829-30.

19. Miller KL, DuBeau CE, Bergmann M, Griffiths DJ, Resnick NM. Quest for a detrusor overactivity index. J
    Urol 2002;167(2 pt 1):578-84; discussion 584-5.

20. DuBeau CE, Khullar V, Versi E. “Unblinding” in randomized controlled drug trials for urinary incontinence:
    Implications for assessing outcomes when adverse effects are evident. Neurourol Urodynam 2005; 24:13-
    20.

21. Fonda D, DuBeau C, Harari D, Palmer M, Ouslander J, Roe B. Incontinence in the Frail Elderly. In:
    Incontinence, 3rd edition. Abrams P, Cardozo L, Khoury S. Wein A, ed. Plymouth, UK:Health Publication
    Ltd. 2005: pp 1163-1239.

22. DuBeau CE. Functional and Overflow Incontinence. In: Multidisciplinary Management of Female Pelvic
    Floor Disorders. Chapple C, Zimmern PE, Brubaker L, Smith ARB, Norton C, Bo K, ed. London:Elsevier
    Inc. 2006: pp65-74.

23. DuBeau CE, Versi E. Outcome measures in women with lower urinary tract symptoms: overactive
    bladder. In: Textbook of Female Urology and Urogynecology, 2nd ed. Cardozo L, Staskin D, ed.
    Abington, UK: Informa Healthcare Inc. 2006: pp429-48.

24. DuBeau CE. Urinary Incontinence. In: Geriatric Review Syllabus, 6th ed, Syllabus/Book 1. New
    York:American Geriatrics Society. 2006: pp184-94.

25. DuBeau CE, Khullar V, Versi E. “Unblinding” in randomized controlled drug trials for urinary incontinence:
    Implications for assessing outcomes when adverse effects are evident. Neurourol Urodynam 2005; 24: 13-
    20.

26. DuBeau CE. Estrogen treatment for urinary incontinence: never, now, or in the future? [editorial] JAMA
    2005; 293:998-1001.

27. DuBeau CE. Urinary incontinence in nursing home patients: Are we FIT to be tied? [editorial] J Amer
    Geriatr Soc 2005; 55:1254-6.

28. DuBeau C. The aging lower urinary tract. J Urol 2006; 175(3 Pt 2):S11-5.

29. DuBeau CE, Simon S, Morris JN. Impact of urinary incontinence on quality of life in nursing home
    residents. J Amer Geriatr Soc 2006; 54: 1325-33.

30. Arora VM, Johnson M, Olson J, Podrazik PM, Levine S, DuBeau CE, Sachs GA, Meltzer DO. Using ACOVE Quality Indicators to Measure Quality of Hospital Care for Vulnerable Elders. J Am Geriatr Soc 31. 2007; 55:1705-11; doi:10.1111/j.1532-5415.2007.01444.x

31. Chapple C, DuBeau C, Ebinger U, Rekeda L,Viegas A. Darifenacin treatment of patients over 65 years with overactive bladder: results of a randomized, controlled, 12-week trial. Curr Med Res Opinion, 2007, PMID: 17706004.

32. DuBeau CE. Therapeutic/pharmacologic approaches to urinary incontinence in older adults. Clin Pharm Ther 2009; 85:98-102.

33. DuBeau C, Johnson T, Kuchel G, Palmer M, Wagg A. Urinary incontinence in frail elderly. In: Incontinence, 4th ed. Report of the 4th International Consultation on Incontinence. Abrams P, Cardozo L, Khoury S. Wein A, ed. Plymouth, UK:Health Publication Ltd. 2009: pp 961-1024.

3. Research Support
   Ongoing:
   Educational grant 01/01/09 – 12/31/012
   “Integrated Geriatrics Education: A Model Curriculum across the Medical Education Continuum”
   Agency: Reynolds Foundation
   Co-PIs: M Pugnaire and JH Gurwitz
   Role: Co-I
   Objectives: 1) To create an enhanced integrated educational program in geriatrics spanning UME, GME, and CPE; 2) develop a core Geriatrics Education Resource Center; and 3) enhance the training of clinician educators at all levels around the principles and practice of geriatrics.

Completed:
Educational grant
Geriatric Urology Training at the University of Chicago 07/01/07 – 06/30/09
Agency: American Geriatrics Society/John A. Hartford Foundation
Role: Co-PI

Research Grant
Department of Medicine Excellence in Medical Education and ClinicalCare Award 07/01/08 – 06/30/10
National Learners’ Needs Assessment and Development of Knowledge Test for Urology Resident Training in Geriatric Urology
Agency: University of Chicago Department of Medicine
Role: PI

Educational grant
“Curriculum for the Hospitalized Aging Medical Patient (CHAMP)” 09/01/03 - 08/31/07
Agency: Reynolds Foundation
Objectives: 1) To implement a faculty development program for all geriatricians, all hospitalists, and the majority of general internists that will enhance their geriatric knowledge, improve their clinical teaching, and tailor their approach to existing realities of inpatient care and changes in the educational environment.
2) To develop a comprehensive curriculum that incorporates essential principles of geriatric inpatient care suitable to fit a one-month inpatient rotation. 3) To vertically integrate expanded geriatrics content in the first two years of medical school training with greater geriatrics clinical training in the third year clerkship and enhanced elective offerings in the fourth year. 4) To adapt the faculty development program and inpatient curriculum for export.
Role:

Research Grant 10/110/05 – 10/10/07
Agency: Pfizer, Inc
Patient expectations and outcomes in the UITN BE-DRI study
Objectives: To examine patients’ overall expectations of behavioral and drug therapy for urinary incontinence and to determine whether these expectations have an effect on their perception of improvement after treatment.
Role: PI